3-(N-tert-butyl-N-tert-butyldimethylsiloxyamino)-4'-[bis(4-methoxyphenyl)amino]benzophenone

Base Information

• Chemical Name: 3-(N-tert-butyl-N-tert-butyldimethylsiloxyamino)-4'-[bis(4-methoxyphenyl)amino]benzophenone
• CAS No.: 1352707-74-4
• Molecular Formula: C₃₇H₄₆N₂O₄Si
• Molecular Weight: 610.869
• Mol file: 1352707-74-4.mol

Synonyms:3-(N-tert-butyl-N-tert-butyldimethylsiloxyamino)-4'-[bis(4-methoxyphenyl)amino]benzophenone

Chemical Property of 3-(N-tert-butyl-N-tert-butyldimethylsiloxyamino)-4'-[bis(4-methoxyphenyl)amino]benzophenone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(N-tert-butyl-N-tert-butyldimethylsiloxyamino)-4'-[bis(4-methoxyphenyl)amino]benzophenone

There total 2 articles about 3-(N-tert-butyl-N-tert-butyldimethylsiloxyamino)-4'-[bis(4-methoxyphenyl)amino]benzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

N-3-bromophenyl-N-tert-butyl-N-tert-butyldimethylsiloxyamine (233584-39-9) + 4-{bis(4-methoxyphenyl)amino}benzonitrile (496916-94-0) → 3-(N-tert-butyl-N-tert-butyldimethylsiloxyamino)-4'-[bis(4-methoxyphenyl)amino]benzophenone (1352707-74-4)

Guidance literature:

N-3-bromophenyl-N-tert-butyl-N-tert-butyldimethylsiloxyamine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

4-{bis(4-methoxyphenyl)amino}benzonitrile; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 2.5h; Inert atmosphere;

With water; In tetrahydrofuran; hexane;

DOI:10.1016/j.poly.2011.02.046

Reference yield:

1,3-dibromobenzene (108-36-1) → 3-(N-tert-butyl-N-tert-butyldimethylsiloxyamino)-4'-[bis(4-methoxyphenyl)amino]benzophenone (1352707-74-4)

Guidance literature:

Multi-step reaction with 3 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.75 h / -78 °C / Inert atmosphere

1.2: 5.5 h / -78 - 20 °C / Inert atmosphere

2.1: 1H-imidazole / N,N-dimethyl-formamide / 16 h / 40 °C / Inert atmosphere

3.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere

3.2: 2.5 h / -78 - 20 °C / Inert atmosphere

With 1H-imidazole; n-butyllithium; In tetrahydrofuran; hexane; N,N-dimethyl-formamide;

DOI:10.1016/j.poly.2011.02.046

Reference yield:

3-(N-tert-butyl-N-tert-butyldimethylsiloxyamino)-4'-[bis(4-methoxyphenyl)amino]benzophenone (1352707-74-4) → 1,2-bis[3-(N-tert-butyl-N-tert-butyldimethylsiloxyamino)phenyl]-1,2-bis[4-{N,N-bis(4-methoxyphenyl)amino}phenyl]ethylene (1352707-76-6) + 1,2-bis[3-(N-tert-butyl-N-tert-butyldimethylsiloxyamino)phenyl]-1,2-bis[4-{N,N-bis(4-methoxyphenyl)amino}phenyl]ethylene (1352707-75-5)

Guidance literature:

With pyridine; titanium(IV) chloride tetrahydrofuran; zinc; In tetrahydrofuran; at -10 ℃; for 16.3h; optical yield given as %de; Reflux;

DOI:10.1016/j.poly.2011.02.046

upstream raw materials:

1,3-dibromobenzene

N-3-bromophenyl-N-tert-butyl-N-tert-butyldimethylsiloxyamine

4-{bis(4-methoxyphenyl)amino}benzonitrile

Downstream raw materials:

1,2-bis[3-(N-tert-butyl-N-oxylamino)phenyl]-1,2-bis[4-{N,N-bis(4-methoxyphenyl)amino}phenyl]ethylene

1,2-bis[3-(N-tert-butyl-N-tert-butyldimethylsiloxyamino)phenyl]-1,2-bis[4-{N,N-bis(4-methoxyphenyl)amino}phenyl]ethylene

1,2-bis[3-(N-tert-butyl-N-tert-butyldimethylsiloxyamino)phenyl]-1,2-bis[4-{N,N-bis(4-methoxyphenyl)amino}phenyl]ethylene

1,2-bis[3-(N-tert-butyl-N-hydroxyamino)phenyl]-1,2-bis[4-{N,N-bis(4-methoxy-phenyl)amino}phenyl]ethylene