4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-{3-[(dimethylamino)methyl]phenyl}-2-pyrimidinamine

Base Information

Chemical Name:4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-{3-[(dimethylamino)methyl]phenyl}-2-pyrimidinamine
CAS No.:941318-47-4
Molecular Formula:C₂₆H₂₅N₇
Molecular Weight:435.531
Hs Code.:

Synonyms:4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-{3-[(dimethylamino)methyl]phenyl}-2-pyrimidinamine

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Chemical Property of 4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-{3-[(dimethylamino)methyl]phenyl}-2-pyrimidinamine

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Technology Process of 4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-{3-[(dimethylamino)methyl]phenyl}-2-pyrimidinamine

There total 1 articles about 4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-{3-[(dimethylamino)methyl]phenyl}-2-pyrimidinamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 895635-03-7
N-{3-[3-(2-chloro-4-pyrimidinyl)pyrazolo[1,5-a]pyridin-2-yl]phenyl}-2,2,2-trifluoroacetamide

: 27958-77-6
3-((dimethylamino)methyl)aniline

: 941318-47-4
4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-{3-[(dimethylamino)methyl]phenyl}-2-pyrimidinamine

Guidance literature:: N-{3-[3-(2-chloro-4-pyrimidinyl)pyrazolo[1,5-a]pyridin-2-yl]phenyl}-2,2,2-trifluoroacetamide; 3-((dimethylamino)methyl)aniline; hydrogenchloride; In 1,4-dioxane; water; isopropyl alcohol; at 90 ℃; for 96h;

With water; sodium hydrogencarbonate; In 1,4-dioxane; isopropyl alcohol;

Reference yield: 69.0%

: 501-81-5
pyridyl-3-yl-acetic acid

: 941318-47-4
4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-{3-[(dimethylamino)methyl]phenyl}-2-pyrimidinamine

: 941318-74-7
N-(3-{3-[2-({3-[(Dimethylamino)methyl]phenyl}amino)-4-pyrimidinyl]pyrazolo[1,5-a]pyridin-2-yl}phenyl)-2-(3-pyridinyl)acetamide

Guidance literature:: pyridyl-3-yl-acetic acid; 4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-{3-[(dimethylamino)methyl]phenyl}-2-pyrimidinamine; With benzotriazol-1-ol; In tetrahydrofuran; methanol; ISOPROPYLAMIDE; at 20 ℃; for 48h;

In tetrahydrofuran; ISOPROPYLAMIDE;

Reference yield: 68.0%

: 13115-43-0
2-pyridineacetic acid

: 941318-47-4
4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-{3-[(dimethylamino)methyl]phenyl}-2-pyrimidinamine

: 941318-76-9
N-(3-{3-[2-({3-[(Dimethylamino)methyl]-phenyl}amino)-4-pyrimidinyl]pyrazolo[1,5-a]pyridin-2-yl}phenyl)-2-(3-methyl-5-isoxazolyl)acetamide

Guidance literature:: 2-pyridineacetic acid; 4-[2-(3-aminophenyl)pyrazolo[1,5-a]pyridin-3-yl]-N-{3-[(dimethylamino)methyl]phenyl}-2-pyrimidinamine; With benzotriazol-1-ol; In tetrahydrofuran; methanol; ISOPROPYLAMIDE; at 20 ℃; for 48h;

In tetrahydrofuran; ISOPROPYLAMIDE;