4,7-Dimethoxy-2,1,3-benzothiadiazole

Base Information

Chemical Name:4,7-Dimethoxy-2,1,3-benzothiadiazole
CAS No.:75103-55-8
Molecular Formula:C₈H₈N₂O₂S
Molecular Weight:196.23
Hs Code.:
DSSTox Substance ID:DTXSID30503059
Nikkaji Number:J2.941.803I
Wikidata:Q82356570
Mol file:75103-55-8.mol

Synonyms:75103-55-8;4,7-dimethoxy-2,1,3-benzothiadiazole;4,7-Dimethoxybenzo[c][1,2,5]thiadiazole;DTXSID30503059;AKOS006317552

Suppliers and Price of 4,7-Dimethoxy-2,1,3-benzothiadiazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4,7-Dimethoxy-2,1,3-benzothiadiazole

Chemical Property:

Melting Point:125.5-127 °C(Solv: methanol (67-56-1))
Boiling Point:306.7±22.0 °C(Predicted)
PKA:-1.45±0.50(Predicted)
PSA：72.48000
Density:1.330±0.06 g/cm3(Predicted)
LogP:1.70850
XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:196.03064868
Heavy Atom Count:13
Complexity:164

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C2=NSN=C12)OC

Technology Process of 4,7-Dimethoxy-2,1,3-benzothiadiazole

There total 4 articles about 4,7-Dimethoxy-2,1,3-benzothiadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 40328-95-8
2,3-diamino-1,4-dimethoxybenzene

: 75103-55-8
4,7-dimethoxy-2,1,3-bezothiadiazole

Guidance literature:: With pyridine; N-phenylsulfinylamine; for 18h; Reflux;
DOI:10.1021/ol200748c

Reference yield:

: 6945-76-2
1,4-dimethoxy-2,3-dinitrobenzene

: 75103-55-8
4,7-dimethoxy-2,1,3-bezothiadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: palladium on carbon; hydrogen / ethyl acetate / 20 °C / 760.05 Torr

2: pyridine; N-phenylsulfinylamine / 18 h / Reflux

With pyridine; palladium on carbon; hydrogen; N-phenylsulfinylamine; In ethyl acetate;
DOI:10.1021/ol200748c

Reference yield:

: 150-78-7
1,4-dimethoxybezene

: 75103-55-8
4,7-dimethoxy-2,1,3-bezothiadiazole

Guidance literature:: Multi-step reaction with 3 steps

1: nitric acid / 3.5 h / 100 °C / Cooling with ice

2: palladium on carbon; hydrogen / ethyl acetate / 20 °C / 760.05 Torr

3: pyridine; N-phenylsulfinylamine / 18 h / Reflux

With pyridine; palladium on carbon; hydrogen; nitric acid; N-phenylsulfinylamine; In ethyl acetate;
DOI:10.1021/ol200748c