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1,2-Benzenediamine, 3,6-dimethoxy- (also known as 3,6-dimethoxybenzene-1,2-diamine) can be synthesized via hydrogenation of a mixture of ortho- and para-dinitro derivatives of 1,4-dimethoxybenzene in ethyl acetate under palladium catalysis, yielding it as the sole product. 1,2-Benzenediamine, 3,6-dimethoxy- serves as a precursor in the synthesis of heterocyclic derivatives, such as 4,7-dimethoxy-2-methyl-1H-benzimidazole. The diamine structure features two amino groups and two methoxy groups on a benzene ring, making it a useful intermediate in organic synthesis.

40328-95-8

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40328-95-8 Usage

Category

Organic compound

Usage

Production of hair dyes and colorants

Physical state at room temperature

Dark brown solid

Solubility in water

Sparingly soluble

Health hazards

Skin and eye irritant; respiratory irritation upon inhalation

Carcinogenicity

Potential human carcinogen

Allergic reactions

Linked to allergic reactions in some individuals

Regulatory status

Use regulated in many countries

Precautions

Necessary to avoid exposure

Check Digit Verification of cas no

The CAS Registry Mumber 40328-95-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 4,0,3,2 and 8 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 40328-95:
(7*4)+(6*0)+(5*3)+(4*2)+(3*8)+(2*9)+(1*5)=98
98 % 10 = 8
So 40328-95-8 is a valid CAS Registry Number.

40328-95-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3-diamino-1,4-dimethoxybenzene

1.2 Other means of identification

Product number -
Other names 1,2-diamino-3,6-dimethoxybenzene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:40328-95-8 SDS

40328-95-8Relevant academic research and scientific papers

Synthesis and Photophysical Properties of Porphyrin-Functionalized Molecular Clips

Reek, Joost N. H.,Rowan, Alan E.,Crossley, Maxwell J.,Nolte, Roeland J. M.

, p. 6653 - 6663 (1999)

Different clip-shaped receptor molecules functionalized at one side-wall with a porphyrin unit have been synthesized by a condensation involving a diamino glucoluril derivative and a porphyrin dione. A similar condensation reaction with a porphyrin tetrao

Synthesis, anticancer activity and UPLC analysis of the stability of some New Benzimidazole-4,7-dione derivatives

Blaszczak-Swiatkiewicz, Katarzyna,Almeida, Diogo Correia,De Jesus Perry, Maria,Mikiciuk-Olasik, Elzbieta

, p. 400 - 413 (2014)

In this work, a sensitive analytical method to study the stability of two new series of synthesized heterocyclic compounds, the benzimidazole-4,7-diones 5 and N-oxide benzimidazole-4,7-dione derivatives 6 was established and validated. These derivatives w

Synthesis of 3,6-dimethoxybenzene-1,2-diamine and of 4,7-dimethoxy-2- methyl-1H-benzimidazole

Besset, Tatiana,Morin, Christophe

, p. 1753 - 1756 (2009)

Hydrogenation of a mixture of ortho- and para-dinitro derivatives of 1,4-dimethoxybenzene in ethyl acetate under palladium catalysis, allows 3,6-dimethoxybenzene-1,2-diamine to be isolated as the sole product; this diamine is then converted into 4,7-dimet

Multispectroscopic and theoretical studies on rapid, selective and sensitive visual sensing of cyanide ion in aqueous solution by receptors possessing varying HBD property

Raja Lakshmi,Manivannan,Jayasudha,Elango, Kuppanagounder P.

, p. 2807 - 2821 (2018)

Three new benzoquinone–imidazole ensembles possessing varying number (0, 1 and 2) of electron-withdrawing bromo substituents on the quinone ring have been designed, synthesized, characterized and employed as receptors in cyanide sensing. These receptors c

New benzimidazolequinones as trypanosomicidal agents

López-Lira, Claudia,Tapia, Ricardo A.,Herrera, Alejandra,Lapier, Michel,Maya, Juan D.,Soto-Delgado, Jorge,Oliver, Allen G.,Graham Lappin,Uriarte, Eugenio

, (2021/05/26)

Herein, the design and synthesis of new 2-phenyl(pyridinyl)benzimidazolequinones and their 5-phenoxy derivatives as potential anti-Trypanosoma cruzi agents are described. The compounds were evaluated in vitro against the epimastigotes and trypomastigote f

Anthrathiadiazole Derivatives: Synthesis, Physical Properties and Two-photon Absorption

Fan, Mingxuan,Chen, Guangsheng,Xiang, Yu,Li, Junbo,Yu, Xianglin,Zhang, Wenying,Long, Xueting,Xu, Liang,Wu, Jinjun,Xu, Ze,Zhang, Qichun

, p. 10898 - 10902 (2021/06/28)

Anthrathiadiazole is a key synthon for the construction of large azaacenes, however, the attachment of different substituents onto the skeleton of anthrathiadiazole is difficult but highly desirable because it could be easy to enrich the structures of aza

Chiral tetrahydrofuran oxazine fused benzimidazole-4, 7-diketone derivative as well as preparation method and application thereof

-

, (2020/11/23)

The invention discloses a chiral tetrahydrofuran oxazine fused benzimidazole-4, 7-diketone derivative and a preparation method and application thereof, and belongs to the field of sugar chemistry andmedicinal chemistry. The chiral tetrahydrofuran oxazine

Identification of ortho-naphthoquinones as anti-AML agents by highly efficient oxidation of phenols

Huang, Huidan,Yan, Ming,Chen, Jianqiu,Yuan, Biao,Chen, Guitang,Cheng, Shujie,Huang, Dechun,Gao, Zhen,Cao, Chongjiang

, p. 97 - 102 (2019/01/28)

A straightforward method for synthesizing ortho-naphthoquinones was identified using an easily available cobalt–Schiff base complex. Efficient oxidation of phenols to ortho-naphthoquinones was useful in obtaining compounds with potent biological activity

A pyridyl-benzimidazole based molecular luminescent turnstile

Godde, Bérangère,Ritaine, Dialia,Jouaiti, Abdelaziz,Mauro, Matteo,Hosseini, Mir Wais

, p. 7810 - 7815 (2018/05/24)

A molecular turnstile T1 based on a luminescent pyridyl-benzimidazole stator and a rotor containing a pyridyl coordinating site is designed and its multi-step synthesis is described. The turnstile T1 undergoes free rotation of the rotor around the stator.

Light-actuated resorcin[4]arene cavitands

García-López, Víctor,Mili?, Jovana V.,Zalibera, Michal,Neshchadin, Dmytro,Kuss-Petermann, Martin,Ruhlmann, Laurent,Nomrowski, Julia,Trapp, Nils,Boudon, Corinne,Gescheidt, Georg,Wenger, Oliver S.,Diederich, Fran?ois

, p. 5615 - 5626 (2018/08/24)

A light-actuated resorcin[4]arene cavitand equipped with two quinone (Q) and two opposite Ru(II)-based photosensitizing walls was synthesized and investigated. The cavitand is capable of switching from an open to a contracted conformation upon reduction of the two Q to the corresponding SQ radical anions by intramolecular photoinduced electron transfer in the presence of a sacrificial donor. The molecular switch was investigated by cyclic and rotating disc voltammetry, UV–Vis–NIR spectroelectrochemistry, transient absorption, NMR, and EPR spectroscopy. This study provides the basis for the development of future light-activated switches and molecular actuating nanodevices.

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