(Z)-2-[2-(N-benzylpropionamido)-3-methylbutanamido]vinyl acetate

Base Information

• Chemical Name: (Z)-2-[2-(N-benzylpropionamido)-3-methylbutanamido]vinyl acetate
• CAS No.: 912350-77-7
• Molecular Formula: C₁₉H₂₆N₂O₄
• Molecular Weight: 346.426
• Mol file: 912350-77-7.mol

Synonyms:(Z)-2-[2-(N-benzylpropionamido)-3-methylbutanamido]vinyl acetate

Chemical Property of (Z)-2-[2-(N-benzylpropionamido)-3-methylbutanamido]vinyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-2-[2-(N-benzylpropionamido)-3-methylbutanamido]vinyl acetate

There total 2 articles about (Z)-2-[2-(N-benzylpropionamido)-3-methylbutanamido]vinyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-isocyanovinyl acetate + isobutylidenebenzylamine (22483-21-2) + propionic acid (802294-64-0,79-09-4) → (Z)-2-[2-(N-benzylpropionamido)-3-methylbutanamido]vinyl acetate (912350-77-7)

Guidance literature:

isobutylidenebenzylamine; propionic acid; In methanol; at 20 ℃; for 0.0833333h;

2-isocyanovinyl acetate; In methanol; at 20 ℃; for 12h;

DOI:10.1021/ja0644374

Reference yield:

benzylamine (100-46-9) → (Z)-2-[2-(N-benzylpropionamido)-3-methylbutanamido]vinyl acetate (912350-77-7)

Guidance literature:

Multi-step reaction with 2 steps

1.1: methanol / 0.17 h / 20 °C

2.1: methanol / 0.08 h / 20 °C

2.2: methanol / 12 h / 20 °C

In methanol; 2.2: Ugi reaction;

DOI:10.1021/ja0644374

Reference yield: 100.0%

(Z)-2-[2-(N-benzylpropionamido)-3-methylbutanamido]vinyl acetate (912350-77-7) + methanol (67-56-1) → metyl 2-(N-benzylpropionamido)-3-methylbutanoate

Guidance literature:

With hydrogenchloride; at 55 ℃; for 3h;

DOI:10.1021/ja0644374

upstream raw materials:

isobutylidenebenzylamine

propionic acid

benzylamine