Ethyl 2-[1-benzyl-6-(4-trifluoromethoxylphenyl)-1H-indol-3-yl]-2-oxoacetate

Base Information

Chemical Name:Ethyl 2-[1-benzyl-6-(4-trifluoromethoxylphenyl)-1H-indol-3-yl]-2-oxoacetate
CAS No.:481630-32-4
Molecular Formula:C₂₆H₂₀F₃NO₄
Molecular Weight:467.444
Hs Code.:

Synonyms:Ethyl 2-[1-benzyl-6-(4-trifluoromethoxylphenyl)-1H-indol-3-yl]-2-oxoacetate

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Chemical Property of Ethyl 2-[1-benzyl-6-(4-trifluoromethoxylphenyl)-1H-indol-3-yl]-2-oxoacetate

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Technology Process of Ethyl 2-[1-benzyl-6-(4-trifluoromethoxylphenyl)-1H-indol-3-yl]-2-oxoacetate

There total 2 articles about Ethyl 2-[1-benzyl-6-(4-trifluoromethoxylphenyl)-1H-indol-3-yl]-2-oxoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 79-37-8
oxalyl dichloride

: 481630-31-3
1-Benzyl-6-(4-trifluoromethoxylphenyl)-1H-indole

: 481630-32-4
Ethyl 2-[1-benzyl-6-(4-trifluoromethoxylphenyl)-1H-indol-3-yl]-2-oxoacetate

Guidance literature:: In tetrahydrofuran; ethanol; hexane; ethyl acetate;

Reference yield: 84.0%

: 481630-32-4
Ethyl 2-[1-benzyl-6-(4-trifluoromethoxylphenyl)-1H-indol-3-yl]-2-oxoacetate

Guidance literature:

Reference yield: 82.0%

: 481630-32-4
Ethyl 2-[1-benzyl-6-(4-trifluoromethoxylphenyl)-1H-indol-3-yl]-2-oxoacetate

: {1-Benzyl-6-[4-(trifluoromethoxy)phenyl]-1H-indol-3-yl}(oxo)acetic acid

Guidance literature:: Ethyl 2-[1-benzyl-6-(4-trifluoromethoxylphenyl)-1H-indol-3-yl]-2-oxoacetate; With potassium hydroxide; water; In tetrahydrofuran; at 20 ℃; for 3.5h;

With hydrogenchloride; In tetrahydrofuran; water;