(5-Fluoro-2-hydroxyphenyl)acetonitrile

Base Information

Chemical Name:(5-Fluoro-2-hydroxyphenyl)acetonitrile
CAS No.:709025-81-0
Molecular Formula:C8H6 F N O
Molecular Weight:151.1377432
Hs Code.:
DSSTox Substance ID:DTXSID70435224
Wikidata:Q82250004
Mol file:709025-81-0.mol

Synonyms:709025-81-0;(5-Fluoro-2-hydroxyphenyl)acetonitrile;SCHEMBL3067018;DTXSID70435224;2-(5-Fluoro-2-hydroxyphenyl)acetonitrile;EN300-1866309

Suppliers and Price of (5-Fluoro-2-hydroxyphenyl)acetonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of (5-Fluoro-2-hydroxyphenyl)acetonitrile

Chemical Property:

PSA：44.02000
LogP:1.59738
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:151.043341977
Heavy Atom Count:11
Complexity:174

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1F)CC#N)O

Technology Process of (5-Fluoro-2-hydroxyphenyl)acetonitrile

There total 5 articles about (5-Fluoro-2-hydroxyphenyl)acetonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₀H₈FNO₂

: 709025-81-0
2-hydroxy-5-fluorophenyl-acetonitrile

Guidance literature:: With hydrogenchloride; In water; ethyl acetate;

Reference yield:

: 773837-37-9
sodium cyanide

: 1260902-19-9
C₇H₆BrFO

: 709025-81-0
2-hydroxy-5-fluorophenyl-acetonitrile

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃; for 72h;

Reference yield:

: 700381-18-6
2-(bromomethyl)-4-fluoro-1-methoxybenzene

: 709025-81-0
2-hydroxy-5-fluorophenyl-acetonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: boron tribromide / dichloromethane / 21 h / -78 - 20 °C

2: N,N-dimethyl-formamide / 72 h / 20 °C

With boron tribromide; In dichloromethane; N,N-dimethyl-formamide;