Propanedioic acid, 2-[(2E)-3-chloro-2-propen-1-yl]-2-(1-methylethyl)-, 1,3-dimethyl ester

Base Information

Chemical Name:Propanedioic acid, 2-[(2E)-3-chloro-2-propen-1-yl]-2-(1-methylethyl)-, 1,3-dimethyl ester
CAS No.:705259-97-8
Molecular Formula:C11H17 Cl O4
Molecular Weight:248.7
Hs Code.:
Mol file:705259-97-8.mol

Synonyms:Propanedioicacid, [(2E)-3-chloro-2-propenyl](1-methylethyl)-, dimethyl ester (9CI)

Suppliers and Price of Propanedioic acid, 2-[(2E)-3-chloro-2-propen-1-yl]-2-(1-methylethyl)-, 1,3-dimethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 9 raw suppliers

Chemical Property of Propanedioic acid, 2-[(2E)-3-chloro-2-propen-1-yl]-2-(1-methylethyl)-, 1,3-dimethyl ester

Chemical Property:

PSA：52.60000
LogP:2.11740

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Propanedioic acid, 2-[(2E)-3-chloro-2-propen-1-yl]-2-(1-methylethyl)-, 1,3-dimethyl ester

There total 1 articles about Propanedioic acid, 2-[(2E)-3-chloro-2-propen-1-yl]-2-(1-methylethyl)-, 1,3-dimethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 51122-91-9
dimethyl isopropylmalonate

: 10061-02-6
(E)-1,3-dichloro-prop-1-ene

: 705259-97-8
dimethyl 2-[(2E)-3-chloro-2-propenyl]-2-isopropyl malonate

Guidance literature:: dimethyl isopropylmalonate; With potassium hydroxide; tetrabutylammomium bromide; In toluene; for 0.166667h;

(E)-1,3-dichloro-prop-1-ene; In toluene; at 30 - 35 ℃; for 4h; Product distribution / selectivity;

Reference yield: 71.0%

: 705259-97-8
dimethyl 2-[(2E)-3-chloro-2-propenyl]-2-isopropyl malonate

: 475562-17-5
methyl (4E)-5-chloro-2-isopropyl-4-pentenoate

Guidance literature:: With water; In sulfolane; at 190 ℃; for 5h; Product distribution / selectivity;

Reference yield:

: 705259-97-8
dimethyl 2-[(2E)-3-chloro-2-propenyl]-2-isopropyl malonate

: 324519-68-8
trans-(2S)-5-chloro-2-isopropyl-N,N-dimethyl-4-pentenamide

Guidance literature:: Multi-step reaction with 3 steps

1.1: potassium hydroxide / 2-methoxy-ethanol / 3 h / 120 °C

1.2: pH 2

1.3: 65 °C

2.1: sodium hydroxide / Esterase V enzime / 24 h / pH ~ 10 / Sodium carbonate buffer; Resolution of racemate; Enzymatic reaction

3.1: isopropylmagnesium chloride / tetrahydrofuran / 30 - 35 °C / Inert atmosphere

With isopropylmagnesium chloride; potassium hydroxide; sodium hydroxide; Esterase V enzime; In tetrahydrofuran; 2-methoxy-ethanol;