Technology Process of 10-ethyl-10H-3,7-di(3-hydroxyphenyl)phenothiazine
There total 5 articles about 10-ethyl-10H-3,7-di(3-hydroxyphenyl)phenothiazine which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); potassium carbonate;
In
1,2-dimethoxyethane; water;
at 95 ℃;
for 14h;
Inert atmosphere;
DOI:10.1016/j.tetlet.2012.12.068
- Guidance literature:
-
Multi-step reaction with 2 steps
1: acetic acid / 16 h / 20 °C / Inert atmosphere
2: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / water; 1,2-dimethoxyethane / 14 h / 95 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); potassium carbonate; acetic acid;
In
1,2-dimethoxyethane; water;
2: |Suzuki Coupling;
DOI:10.1016/j.tetlet.2012.12.068
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: potassium tert-butylate / tetrahydrofuran / 20 °C / Inert atmosphere
2.1: bromine; acetic acid / 20 °C / Inert atmosphere
3.1: n-butyllithium / tetrahydrofuran / 0.33 h / -78 °C / Inert atmosphere
3.2: 0.5 h / -78 °C / Inert atmosphere
4.1: acetic acid / 16 h / 20 °C / Inert atmosphere
5.1: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / water; 1,2-dimethoxyethane / 14 h / 95 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); n-butyllithium; potassium tert-butylate; bromine; potassium carbonate; acetic acid;
In
tetrahydrofuran; 1,2-dimethoxyethane; water;
5.1: |Suzuki Coupling;
DOI:10.1016/j.tetlet.2012.12.068
