N-(5,6,7,8-tetrahydronaphthalen-1-yl)benzamide

Base Information

• Chemical Name: N-(5,6,7,8-tetrahydronaphthalen-1-yl)benzamide
• CAS No.: 79005-34-8
• Molecular Formula: C₁₇H₁₇NO
• Molecular Weight: 251.328
• European Community (EC) Number: 668-153-1
• Mol file: 79005-34-8.mol

Synonyms:N-(5,6,7,8-tetrahydronaphthalen-1-yl)benzamide;79005-34-8;Oprea1_151680;Oprea1_379236;N-(5,6,7,8-TETRAHYDRO-1-NAPHTHYL)BENZAMIDE;SCHEMBL6054998;STK022477;AKOS005379362;NCGC00330616-01;AB01324819-02

Chemical Property of N-(5,6,7,8-tetrahydronaphthalen-1-yl)benzamide

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 251.131014166
• Heavy Atom Count: 19
• Complexity: 308

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-(5,6,7,8-TETRAHYDRO-1-NAPHTHYL)BENZAMIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCC2=C(C1)C=CC=C2NC(=O)C3=CC=CC=C3

Technology Process of N-(5,6,7,8-tetrahydronaphthalen-1-yl)benzamide

There total 1 articles about N-(5,6,7,8-tetrahydronaphthalen-1-yl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1-amino-5,6,7,8-tetrahydronaphthalene (2217-41-6) + benzoyl chloride (98-88-4) → N-benzoyl-1-amino-5,6,7,8-tetrahydronaphthalene (79005-34-8)

Guidance literature:

With potassium carbonate; In toluene; 1) reflux, 3 h, 2) room temperature, 16 h;

DOI:10.1021/jo00335a038

Reference yield: 41.0%

N-benzoyl-1-amino-5,6,7,8-tetrahydronaphthalene (79005-34-8) → 2-phenyl-1,3,4,5-tetrahydrobenzindole (78987-24-3)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at 0 ℃; for 18h;

DOI:10.1021/jo00335a038

upstream raw materials:

1-amino-5,6,7,8-tetrahydronaphthalene

benzoyl chloride

Downstream raw materials:

2-phenyl-1,3,4,5-tetrahydrobenzindole