2,2,2-Trifluoro-1-(2-nitrophenyl)ethanol

Base Information

Chemical Name:2,2,2-Trifluoro-1-(2-nitrophenyl)ethanol
CAS No.:700362-32-9
Molecular Formula:C8H6 F3 N O3
Molecular Weight:221.136
Hs Code.:
DSSTox Substance ID:DTXSID50595931
Nikkaji Number:J2.040.798K
Mol file:700362-32-9.mol

Synonyms:2,2,2-trifluoro-1-(2-nitrophenyl)ethanol;700362-32-9;2,2,2-Trifluoro-1-(2-nitrophenyl)ethan-1-ol;SCHEMBL6723797;Benzenemethanol, 2-nitro-alpha-(trifluoromethyl)- (9CI);DTXSID50595931;MFCD18825460;AKOS016015155;SY249792;DB-285426;CS-0454987;2-Nitro-alpha-(trifluoromethyl)benzyl Alcohol;EN300-362977;F93874;1,1,1-trifluoro-2-hydroxy-2-(2-nitrophenyl)ethane;J-506719;BENZENEMETHANOL, 2-NITRO-ALPHA-(TRIFLUOROMETHYL)-

Suppliers and Price of 2,2,2-Trifluoro-1-(2-nitrophenyl)ethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2,2,2-Trifluoro-1-(2-nitrophenyl)ethanol 95+%
1g
$ 377.00

American Custom Chemicals Corporation
2,2,2-TRIFLUORO-1-(2-NITROPHENYL)ETHANOL 95.00%
5MG
$ 503.02

Alichem
2,2,2-Trifluoro-1-(2-nitrophenyl)ethanol
1g
$ 400.00

AK Scientific
2,2,2-Trifluoro-1-(2-nitrophenyl)ethanol
5g
$ 1680.00

Total 10 raw suppliers

Chemical Property of 2,2,2-Trifluoro-1-(2-nitrophenyl)ethanol

Chemical Property:

Boiling Point:327.3±42.0 °C(Predicted)
PKA:11.32±0.10(Predicted)
PSA：66.05000
Density:1.486±0.06 g/cm3(Predicted)
LogP:2.71370
XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:221.02997754
Heavy Atom Count:15
Complexity:238

Purity/Quality:

≥95% ^*data from raw suppliers

2,2,2-Trifluoro-1-(2-nitrophenyl)ethanol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C(C(F)(F)F)O)[N+](=O)[O-]

Technology Process of 2,2,2-Trifluoro-1-(2-nitrophenyl)ethanol

There total 4 articles about 2,2,2-Trifluoro-1-(2-nitrophenyl)ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 552-89-6
2-nitro-benzaldehyde

: 700362-32-9
2,2,2-trifluoro-1-(2-nitrophenyl) ethanol

Guidance literature:: (trifluoromethyl)trimethylsilane; 2-nitro-benzaldehyde; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 4h;

With water; In N,N-dimethyl-formamide; for 4h; Acidic conditions;
DOI:10.1016/j.tetlet.2013.06.045

Reference yield: 76.0%

: o-nitrobenzaldehyde 1-iodo-4-methoxybenzene

: 81290-20-2
(trifluoromethyl)trimethylsilane

: 700362-32-9
2,2,2-trifluoro-1-(2-nitrophenyl) ethanol

Guidance literature:: o-nitrobenzaldehyde 1-iodo-4-methoxybenzene; (trifluoromethyl)trimethylsilane; In tetrahydrofuran; at 0 ℃; for 0.166667h; Inert atmosphere; Sealed tube;

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere; Sealed tube;

With tetrabutyl ammonium fluoride; water; In tetrahydrofuran; at 0 - 20 ℃; Inert atmosphere; Sealed tube;
DOI:10.1021/jo301477s