1H-1,2,3-Triazole-1-ethanol

Base Information

• Chemical Name: 1H-1,2,3-Triazole-1-ethanol
• CAS No.: 74731-63-8
• Molecular Formula: C4H7N3O
• Molecular Weight: 113.119
• Hs Code.: 2933990090
• European Community (EC) Number: 824-951-3
• DSSTox Substance ID: DTXSID50433662
• Wikidata: Q82247860
• Mol file: 74731-63-8.mol

Synonyms:74731-63-8;1H-1,2,3-Triazole-1-ethanol;2-(1H-1,2,3-TRIAZOL-1-YL)ETHANOL;2-(triazol-1-yl)ethanol;1H-1,2,3 Triazole-1-ethanol;2-(1H-1,2,3-TRIAZOL-1-YL)ETHAN-1-OL;2-(1,2,3-triazol-1-yl)ethanol;2-(1-triazolyl)ethanol;1-(2-hydroxyethyl)triazole;SCHEMBL255015;DTXSID50433662;PKHVUMMJMYKRNO-UHFFFAOYSA-N;AMY31719;AKOS006277572;2-(1,2,3-triazol-1-yl)-ethan-1-ol;CS-16316;2-(1H-[1,2,3]triazol-1-yl)-ethanol;2-(1H-[1,2,3]-triazol-1-yl)-ethanol;2-[1,2,3]TRIAZOL-1-YL-ETHANOL;1H-1,2,3 triazole-1-ethanol, AldrichCPR;CS-0095270;FT-0641536;EN300-760994;N16844;A838209

Chemical Property of 1H-1,2,3-Triazole-1-ethanol

Chemical Property:

• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.602
• Boiling Point: 270.981 °C at 760 mmHg
• PKA: 13.77±0.10(Predicted)
• Flash Point: 117.685 °C
• PSA: 50.94000
• Density: 1.322 g/cm³
• LogP: -0.72960
• XLogP3: -1.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 113.058911855
• Heavy Atom Count: 8
• Complexity: 68.3

Purity/Quality:

98%,99%, ^*data from raw suppliers

1H-1,2,3Triazole-1-ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN(N=N1)CCO
• Uses: 1H-1,2,3 Triazole-1-ethanol is used as a corrosion inhibitor; abrasive material for flatting metal layers,

Technology Process of 1H-1,2,3-Triazole-1-ethanol

There total 5 articles about 1H-1,2,3-Triazole-1-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-azidoethanol (1517-05-1) + acetylene (74-86-2,25067-58-7) → 2-(1,2,3-triazol-1-yl)-ethan-1-ol (74731-63-8)

Guidance literature:

at 110 - 120 ℃; under 9120 - 10640 Torr;

DOI:10.1007/BF00503205

Reference yield: 64.2%

1-(β-hydroxyethyl)-1,2,3-triazole-4-carboxylic acid (74731-49-0) → 2-(1,2,3-triazol-1-yl)-ethan-1-ol (74731-63-8)

Guidance literature:

under 5 - 10 Torr; Heating;

Reference yield: 61.0%

difluoroacetaldehyde N-tosylhydrazone + ethanolamine (141-43-5) → 2-(1,2,3-triazol-1-yl)-ethan-1-ol (74731-63-8)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In methanol; at 25 ℃; for 5h;

DOI:10.1016/j.cclet.2021.09.008

upstream raw materials:

1-(β-hydroxyethyl)-1,2,3-triazole-4-carboxylic acid

2-azidoethanol

acetylene

1,2,3-triazole

Downstream raw materials:

1-[2-(4-nitro-benzyloxy)-ethyl]-1H-[1,2,3]triazole

1-[2-(4-allyloxy-2-fluoro-benzyloxy)-ethyl]-1H-[1,2,3]triazole

1-[2-(4-allyloxy-2-methyl-benzyloxy)-ethyl]-1H-[1,2,3]triazole

1-[2-(4-allyloxy-benzyloxy)-ethyl]-1H-[1,2,3]-triazole

Refernces

• 1、 -. "QUINAZOLINE DERIVATIVES". Page/Page column 44. . Retrieved 2010/02/11.
• 2、 Tikhonova, L. G.,Maksikova, A. V.,Serebryakova, E. S.,Kaufman, I. G.,Vereshchagin, L. I.. "NUCLEOPHILIC ADDITION OF HYDROXYMETHYL-1,2,3-TRIAZOLES TO MULTIPLE BOND". . p. 1104 - 1107. Retrieved 2007/10/02.