IMIDAZOLE-1-CARBONYL CHLORIDE

Base Information

• Chemical Name: IMIDAZOLE-1-CARBONYL CHLORIDE
• CAS No.: 74731-19-4
• Molecular Formula: C4H3 Cl N2 O
• Molecular Weight: 130.534
• Hs Code.: 2933290090
• Mol file: 74731-19-4.mol

Synonyms:IMIDAZOLE-1-CARBONYL CHLORIDE

Chemical Property of IMIDAZOLE-1-CARBONYL CHLORIDE

Chemical Property:

• Boiling Point: 258.7±23.0 °C(Predicted)
• PKA: 2.81±0.10(Predicted)
• PSA: 34.89000
• Density: 1.44±0.1 g/cm3(Predicted)
• LogP: 1.09000

Purity/Quality:

99% ^*data from raw suppliers

1H-IMIDAZOLE-1-CARBONYL CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of IMIDAZOLE-1-CARBONYL CHLORIDE

There total 2 articles about IMIDAZOLE-1-CARBONYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

phosgene (75-44-5) + 1-(Trimethylsilyl)imidazole (18156-74-6) → 1-imidazolylcarbonyl chloride (74731-19-4) + 1,1'-carbonyldiimidazole (530-62-1)

Guidance literature:

-50 to -40 deg C, then r.t.;

Reference yield:

→ 1-imidazolylcarbonyl chloride (74731-19-4)

Guidance literature:

Reference yield: 97.8%

1-imidazolylcarbonyl chloride (74731-19-4) + 1-(Trimethylsilyl)imidazole (18156-74-6) → 1,1'-carbonyldiimidazole (530-62-1)

Guidance literature:

at 20 - 35 ℃;

upstream raw materials:

phosgene

1-(Trimethylsilyl)imidazole

Downstream raw materials:

1,1'-carbonyldiimidazole

Refernces

• 1、 Sheludyakov, V. D.,Sheludyakova, S. V.,Kuznetsova, M. G.,Silkina, N. N.,Mironov, V. F.. "REACTIONS OF N-(TRIMETHYLSILYL) DERIVATIVES OF IMIDAZOLE, 3(5)-METHYLPYRAZOLE, 3,5-DIMETHYLPYRAZOLE, BENZOTRIAZOLE, AND BENZIMIDAZOLE WITH CYANOGEN CHLORIDE, CHLOROFORMIC ESTER, AND CARBONYL AND CARBAMOYL CHLORIDES". . p. 705 - 711. Retrieved 2007/10/02.