methyl 6-chloro-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Base Information

Chemical Name:methyl 6-chloro-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate
CAS No.:1336965-97-9
Molecular Formula:C₂₀H₁₅ClF₃NO₃
Molecular Weight:409.792
Hs Code.:

Synonyms:methyl 6-chloro-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

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Chemical Property of methyl 6-chloro-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

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Technology Process of methyl 6-chloro-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

There total 3 articles about methyl 6-chloro-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1336965-95-7
6-chloro-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylic acid

: 74-88-4
methyl iodide

: 1336965-97-9
methyl 6-chloro-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Guidance literature:: 6-chloro-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylic acid; With sodium hydride; In N,N-dimethyl-formamide; for 0.333333h;

methyl iodide; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 454-89-7
3-Trifluoromethylbenzaldehyde

: 1336965-97-9
methyl 6-chloro-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: ethanol / 1 h / Reflux

1.2: 3 h / Reflux

2.1: sodium hydride / N,N-dimethyl-formamide / 0.33 h

2.2: 20 °C

With sodium hydride; In ethanol; N,N-dimethyl-formamide;

Reference yield:

: 13726-14-2
4-chloro-m-anisidine

: 1336965-97-9
methyl 6-chloro-3-methyl-7-(methyloxy)-2-[3-(trifluoromethyl)phenyl]-4-quinolinecarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: ethanol / 1 h / Reflux

1.2: 3 h / Reflux

2.1: sodium hydride / N,N-dimethyl-formamide / 0.33 h

2.2: 20 °C

With sodium hydride; In ethanol; N,N-dimethyl-formamide;