2-(Dicyclohexylphosphino)-1-(2,4,6-trimethyl-phenyl)-1H-imidazole

Base Information

• Chemical Name: 2-(Dicyclohexylphosphino)-1-(2,4,6-trimethyl-phenyl)-1H-imidazole
• CAS No.: 794527-14-3
• Molecular Formula: C₂₄H₃₅N₂P
• Molecular Weight: 382.529
• Hs Code.: 29332900
• Mol file: 794527-14-3.mol

Synonyms:2-(Dicyclohexylphosphino)-1-mesityl-1H-imidazole;Dicyclohexyl(1-mesityl-1H-imidazol-2-yl)phosphine

Chemical Property of 2-(Dicyclohexylphosphino)-1-(2,4,6-trimethyl-phenyl)-1H-imidazole

Chemical Property:

• Melting Point: 109°C
• Boiling Point: 538.2±60.0 °C(Predicted)
• PKA: 4.30±0.10(Predicted)
• PSA: 31.41000
• LogP: 6.57010
• Sensitive.: air sensitive

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-(2,4,6-Trimethylphenyl)-2-(dicyclohexylphosphino)imidazole, min. 95% [cataCXium(R) PlCy] ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Catalyst for coupling reactions of aryl chlorides

Technology Process of 2-(Dicyclohexylphosphino)-1-(2,4,6-trimethyl-phenyl)-1H-imidazole

There total 2 articles about 2-(Dicyclohexylphosphino)-1-(2,4,6-trimethyl-phenyl)-1H-imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

N-(2,4,6-trimethylphenyl)imidazole (25364-44-7) + chlorodicyclohexylphosphane (16523-54-9) → 2-(dicyclohexylphosphino)-1-mesityl-1H-imidazole (794527-14-3)

Guidance literature:

N-(2,4,6-trimethylphenyl)imidazole; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; for 2.5h; Heating;

chlorodicyclohexylphosphane; In hexane; for 1h; Heating;

DOI:10.1002/adsc.200404213

Reference yield: 50.0%

chlorodicyclohexylphosphane (16523-54-9) → 2-(dicyclohexylphosphino)-1-mesityl-1H-imidazole (794527-14-3)

Guidance literature:

N-(2,4,6-trimethylphenyl)imidazole; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; for 2.5h; Heating / reflux;

chlorodicyclohexylphosphane; In hexane; at 60 ℃; for 1h; Heating / reflux;

Reference yield:

dodecacarbonyl-triangulo-triruthenium (15243-33-1) + 2-(dicyclohexylphosphino)-1-mesityl-1H-imidazole (794527-14-3) → C30H35N2O6PRu2

Guidance literature:

In acetonitrile; at 100 ℃; for 1h; Inert atmosphere;

DOI:10.1002/chem.201504051

upstream raw materials:

N-(2,4,6-trimethylphenyl)imidazole

chlorodicyclohexylphosphane