methyl 2-chloro-6-fluoro-N-[(3-methyl-2-thiophene)carbonyl]benzenecarboximidiothioate

Base Information

• Chemical Name: methyl 2-chloro-6-fluoro-N-[(3-methyl-2-thiophene)carbonyl]benzenecarboximidiothioate
• CAS No.: 265652-35-5
• Molecular Formula: C₁₄H₁₁ClFNOS₂
• Molecular Weight: 327.831
• Mol file: 265652-35-5.mol

Synonyms:methyl 2-chloro-6-fluoro-N-[(3-methyl-2-thiophene)carbonyl]benzenecarboximidiothioate

Chemical Property of methyl 2-chloro-6-fluoro-N-[(3-methyl-2-thiophene)carbonyl]benzenecarboximidiothioate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2-chloro-6-fluoro-N-[(3-methyl-2-thiophene)carbonyl]benzenecarboximidiothioate

There total 2 articles about methyl 2-chloro-6-fluoro-N-[(3-methyl-2-thiophene)carbonyl]benzenecarboximidiothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,4-dioxane (123-91-1,28347-88-8,28347-91-3,39449-24-6,54841-74-6) + 3-methyl-2-thiophenecarbonyl chloride (acid chloride) + 2-chloro-6-fluorobenzenecarbothioamide (769-05-1) → methyl 2-chloro-6-fluoro-N-[(3-methyl-2-thiophene)carbonyl]benzenecarboximidiothioate (265652-35-5)

Guidance literature:

With pyridine; dimethyl sulfate; In water;

Reference yield:

3-methylthenoyl chloride (61341-26-2) + 2-chloro-6-fluorothiobenzimidic acid methyl ester hydrogen bromide (503309-13-5) → methyl 2-chloro-6-fluoro-N-[(3-methyl-2-thiophene)carbonyl]benzenecarboximidiothioate (265652-35-5)

Guidance literature:

With pyridine; In 1,2-dichloro-ethane; at 25 ℃;

DOI:10.1021/jf071498s

Reference yield:

methyl 2-chloro-6-fluoro-N-[(3-methyl-2-thiophene)carbonyl]benzenecarboximidiothioate (265652-35-5) + methylhydrazine (60-34-4) → 3-(2-Chloro-6-fluorophenyl)-1-methyl-5-(3-methyl-thien-2-yl)-1H-1,2,4-triazole (214407-93-9)

Guidance literature:

In 1,4-dioxane; ethanol; water;

upstream raw materials:

1,4-dioxane

2-chloro-6-fluorobenzenecarbothioamide

3-methylthenoyl chloride

2-chloro-6-fluorothiobenzimidic acid methyl ester hydrogen bromide

Downstream raw materials:

3-(2-Chloro-6-fluorophenyl)-1-methyl-5-(3-methyl-thien-2-yl)-1H-1,2,4-triazole