N-Cbz-O-MOM-ΔTyr-OH

Base Information

• Chemical Name: N-Cbz-O-MOM-ΔTyr-OH
• CAS No.: 108158-14-1
• Molecular Formula: C₁₉H₁₉NO₆
• Molecular Weight: 357.363
• Mol file: 108158-14-1.mol

Synonyms:N-Cbz-O-MOM-ΔTyr-OH

Chemical Property of N-Cbz-O-MOM-ΔTyr-OH

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Cbz-O-MOM-ΔTyr-OH

There total 4 articles about N-Cbz-O-MOM-ΔTyr-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

N-Cbz-O-MOM-ΔTyr-OEt (108158-13-0) → N-Cbz-O-MOM-ΔTyr-OH (108158-14-1)

Guidance literature:

With lithium hydroxide; In 1,4-dioxane;

DOI:10.3987/R-1986-06-1561

Reference yield:

4-methoxymethoxy-benzaldehyde (6515-21-5) → N-Cbz-O-MOM-ΔTyr-OH (108158-14-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 57 percent / EtONa / ethanol / 4 h / 0 °C

2: 95 percent / Al(Hg) / diethyl ether

3: 60 percent / NaOH, n-Bu₄N*HSO₄ / CH₂Cl₂ / 24 h

4: 85 percent / LiOH / dioxane

With lithium hydroxide; sodium hydroxide; aluminum amalgam; sodium ethanolate; tetra(n-butyl)ammonium hydrogensulfate; In 1,4-dioxane; diethyl ether; ethanol; dichloromethane;

DOI:10.3987/R-1986-06-1561

Reference yield:

(Z)-2-Amino-3-(4-methoxymethoxy-phenyl)-acrylic acid ethyl ester (108158-12-9) → N-Cbz-O-MOM-ΔTyr-OH (108158-14-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 60 percent / NaOH, n-Bu₄N*HSO₄ / CH₂Cl₂ / 24 h

2: 85 percent / LiOH / dioxane

With lithium hydroxide; sodium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; In 1,4-dioxane; dichloromethane;

DOI:10.3987/R-1986-06-1561

upstream raw materials:

N-Cbz-O-MOM-ΔTyr-OEt

4-methoxymethoxy-benzaldehyde

(Z)-2-Amino-3-(4-methoxymethoxy-phenyl)-acrylic acid ethyl ester

ethyl 2-azido-(p-methoxymethoxy)cinnamate

Downstream raw materials:

N-carboxy dehydrotyrosine anhydride