6515-21-5

Upstream product

• 109-87-5 Dimethoxymethane 
• 123-08-0 4-hydroxy-benzaldehyde 
• 107-30-2 chloromethyl methyl ether 
• 13057-17-5 bromethyl methyl ether 
• 23639-82-9 p-hydroxybenzaldehyde ethylene glycol acetal 
• 1448638-99-0 2-(4-(methoxymethoxy)phenyl)-1,3-dioxolane 
• 6399-81-1 triphenylphosphine hydrobromide 
• 58765-11-0 4-hydroxybenzaldehyde potassium salt 
• 100-52-7 benzaldehyde 

Downstream Products

• 111797-34-3 2'-hydroxy-3',4',6'-trimethoxy-4-methoxymethoxy-trans-chalcone 
• 108158-11-8 ethyl 2-azido-(p-methoxymethoxy)cinnamate 
• 108440-51-3 1-(4-hydroxyphenyl)-3-hydroxymethyl-4-(1,3-dithian)-6,7-methylenedioxy-2-naphtoic acid lactone 
• 124775-22-0 1-<2-Hydroxy-4-(methoxymethoxy)phenyl>-3-<4-(methoxymethoxy)phenyl>prop-2-en-1-on 
• 110168-73-5 4,2'-bis(methoxymethoxy)-6'-methoxychalcone 
• 115523-91-6 2',4,4'-tris(methoxymethoxy)chalcone 
• 101946-89-8 4,2',6'-tris(methoxymethoxy)chalcone 
• 118160-11-5 tetrakis(methoxymethoxy) isosalipurpol 
• 6515-14-6 4,2'-bis(methoxymethoxy)chalcone 
• 97080-68-7 (Z)-1-(4-Methoxy-2-methoxymethoxy-phenyl)-3-(4-methoxy-phenyl)-propenone 
• 128961-13-7 (E)-1-(2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl)-3-(4-(methoxymethoxy)phenyl)prop-2-en-1-one 
• 148625-90-5 (1E,4E)-1-(3-Methoxy-4-methoxymethoxy-phenyl)-5-(4-methoxymethoxy-phenyl)-penta-1,4-dien-3-one 
• 80613-02-1 Methyl (Z)-2-formylamino-3-(4-methoxymethoxyphenyl)-acrylate 
• 84092-46-6 2-hydroxy-4,4',6-tri(methoxymethoxy)-3-(3,3-dimethylallyl)chalcone 

Relevant academic research and scientific papers

A selective fluorescent sensor for Pb(II) in water

A new fluorescent sensor (1) containing bis(2-pyridylmethyl)amine group as a binding moiety for Pb2+ was developed. Compound 1 shows selective response to Pb2+ over other metal ions in pH 7.0 HEPES buffer solution. The fluorescence i

Discovery of novel 3-(hydroxyalkoxy)-2-alkylchromen-4-one analogs as interleukin-5 inhibitors

A series of novel chromen-4-one analogs 9a-d and 10a-u was designed, synthesized and evaluated for their IL-5 inhibitory activity. Most of the chromen-4-one analogs showed strong inhibitory activity in low micro molar potency. Among them, 5-(cyclohexylmet

NaI-mediated oxidative amidation of benzyl alcohols/aromatic aldehydes to benzamides via electrochemical reaction

In this research, we have developed a mild electrochemical process for oxidative amidation of benzyl alcohols/aromatic aldehydes with cyclic amines into the corresponding benzamides. This electroorganic synthetic method proceeds using NaI as a redox mediator under ambient temperature in undivided cell, providing more than 25 examples of amide products in moderate to good yields. The benefits of this reaction include one-pot synthesis, open air condition, proceed in aqueous media and no requirement of external conducting salt, base and oxidant.

Neuroregenerative Potential of Prenyl- And Pyranochalcones: A Structure-Activity Study

Loss of neuronal tissue is a hallmark of age-related neurodegenerative diseases. Since adult neurogenesis has been confirmed in the human brain, great interest has arisen in substances stimulating the endogenous neuronal regeneration mechanism based on ad

Oxoammonium-Mediated Allylsilane–Ether Coupling Reaction

A new C(sp3)?H functionalization reaction consisting of the oxidative α-allylation of allyl- and benzyl- methyl ethers has been developed. The C?C coupling could be carried out under mild conditions thanks to the use of cheap and green oxoammonium salts. The scope of the reaction was studied over 27 examples, considering the nature of the substituents on the two coupling partners.

Flavanone compound as well as preparation method and application thereof

The invention belongs to the technical field of medicines, and particularly relates to a flavanone compound as well as a preparation method and application thereof. Specifically disclosed is a compound represented by formula (I) or a pharmaceutically acceptable salt thereof. The compound shown in the formula (I) can target hURAT1 and/or GLUT9, so that uric acid excretion is promoted, and the effect of reducing uric acid is achieved. The compound can be used for preparing medicines for treating and/or preventing and/or delaying and/or adjunctively treating and/or treating diseases related to hURAT1/GLUT9 activity, and has a good application prospect in preventing or treating diseases (such as gout, gouty arthritis, uric acid kidney stone and the like) related to hyperuricemia.

Microbial Transformation of Broussochalcones A and B by Aspergillus niger

Broussochalcones A (BCA, 1) and B (BCB, 2) are major bioactive constituents isolated from Broussonetia papyrifera, a polyphenol-rich plant belonging to the family Moraceae. Due to their low yields from natural sources, BCA (1) and BCB (2) were prepared sy

S1P1 AGONIST AND APPLICATION THEREOF

The present invention relates to a class of tricyclic compounds and an application thereof as a sphingosine 1-phosphate type 1 (S1P1) receptor agonist. The invention specifically relates to a compound represented by formula (II), and a tautomer and pharmaceutically acceptable salt of same.

Analogues of 2′-hydroxychalcone with modified C4-substituents as the inhibitors against human acetylcholinesterase

A series of C4-substituted tertiary nitrogen-bearing 2′-hydroxychalcones were designed and synthesised based on a previous mixed type acetylcholinesterase inhibitor. Majority of the 2′-hydroxychalcone analogues displayed a better inhibition against acetyl

Visible light photoredox catalyzed deprotection of 1,3-oxathiolanes

An efficient visible light photoredox catalyzed aerobic deprotection of 1,3-oxathiolanes using organic dye Eosin Y as a photocatalyst is disclosed. The deprotection procedure features the use of a metal-free catalyst, mild conditions, a broad range of substrate scope, and good functional group tolerance. 35 examples were tested under the standard conditions and most of them afforded the deprotected products in modest to high yields.