2-amino-4-(2-chlorophenyl)buta-1,3-diene-1,1,3-tricarbonitrile

Base Information

• Chemical Name: 2-amino-4-(2-chlorophenyl)buta-1,3-diene-1,1,3-tricarbonitrile
• CAS No.: 340994-77-6
• Molecular Formula: C₁₃H₇ClN₄
• Molecular Weight: 254.678
• Mol file: 340994-77-6.mol

Synonyms:2-amino-4-(2-chlorophenyl)buta-1,3-diene-1,1,3-tricarbonitrile

Chemical Property of 2-amino-4-(2-chlorophenyl)buta-1,3-diene-1,1,3-tricarbonitrile

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-amino-4-(2-chlorophenyl)buta-1,3-diene-1,1,3-tricarbonitrile

There total 2 articles about 2-amino-4-(2-chlorophenyl)buta-1,3-diene-1,1,3-tricarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1,1,2,2,-tetracyanoethane (14778-29-1) + 2-chloro-benzaldehyde (89-98-5) → 2-amino-4-(2-chlorophenyl)buta-1,3-diene-1,1,3-tricarbonitrile (340994-77-6)

Guidance literature:

With piperdinium acetate; In ethanol; at 65 - 70 ℃; for 0.166667h;

DOI:10.1134/S1070428014020171

Reference yield:

1,1,3-tricyano-2-amino-1-propene (868-54-2) + 2-chloro-benzaldehyde (89-98-5) → 2-amino-4-(2-chlorophenyl)buta-1,3-diene-1,1,3-tricarbonitrile (340994-77-6)

Guidance literature:

With piperdinium acetate; In isopropyl alcohol; for 0.333333h; Reflux;

DOI:10.1016/j.tetlet.2015.02.081

Reference yield: 96.0%

methanol (67-56-1) + 2-amino-4-(2-chlorophenyl)buta-1,3-diene-1,1,3-tricarbonitrile (340994-77-6) + dimedone (126-81-8) → 4-amino-8,8-dimethyl-2-methoxy-6-oxo-5-(2-chlorophenyl)-5,6,7,8,9,10-hexahydrobenzo[b]-[1,8]-naphthyridine-3-carbonitrile (1586814-54-1)

Guidance literature:

methanol; dimedone; With sodium;

2-amino-4-(2-chlorophenyl)buta-1,3-diene-1,1,3-tricarbonitrile; Reflux;

DOI:10.1134/S1070428014020171

upstream raw materials:

1,1,2,2,-tetracyanoethane

2-chloro-benzaldehyde

1,1,3-tricyano-2-amino-1-propene

Downstream raw materials:

2-{amino[3-(2-chlorophenyl)-2-cyanooxiran-2-yl]methylidene}malononitrile

C₁₃H₆Cl₂N₄

C₁₃H₆BrClN₄

4-amino-8,8-dimethyl-2-methoxy-6-oxo-5-(2-chlorophenyl)-5,6,7,8,9,10-hexahydrobenzo[b]-[1,8]-naphthyridine-3-carbonitrile