(S)-1-methyl-2-phenylsylfanylethylamine

Base Information

• Chemical Name: (S)-1-methyl-2-phenylsylfanylethylamine
• CAS No.: 122673-70-5
• Molecular Formula: C₉H₁₃NS
• Molecular Weight: 167.275
• Mol file: 122673-70-5.mol

Synonyms:(S)-1-methyl-2-phenylsylfanylethylamine

Chemical Property of (S)-1-methyl-2-phenylsylfanylethylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-1-methyl-2-phenylsylfanylethylamine

There total 6 articles about (S)-1-methyl-2-phenylsylfanylethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(S)-N-benzyloxycarbonyl-1-methyl-2-phenylsulfanylethylamine (118682-14-7) → (S)-1-methyl-2-phenylsylfanylethylamine (122673-70-5)

Guidance literature:

With potassium hydroxide; In ethanol; for 17h; Heating;

Reference yield: 56.0%

phenylthiotrimethylsilane (4551-15-9) + (S)-2-methylaziridine (52340-20-2) → (S)-1-methyl-2-phenylsylfanylethylamine (122673-70-5)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 6h; regioselective reaction; Inert atmosphere;

DOI:10.1039/c9nj00657e

Reference yield: 42.0%

(S)-Alaninol (2749-11-3) + diphenyldisulfane (882-33-7) → (S)-1-methyl-2-phenylsylfanylethylamine (122673-70-5)

Guidance literature:

With tributylphosphine; In tetrahydrofuran; at 20 ℃; Schlenk technique; Inert atmosphere;

DOI:10.1016/j.jorganchem.2020.121332

upstream raw materials:

(S)-2,4-dimethyl-2-oxazoline

thiophenol

(S)-N-benzyloxycarbonyl-1-methyl-2-phenylsulfanylethylamine

potassium thiophenolate

Downstream raw materials:

(1S)-1-methyl-N-[(S)-1-phenylethyl]-2-phenylsulfanylethylamine

(1S)-1-methyl-N-[(R)-1-phenylethyl]-2-phenylsulfanylethylamine

(S)-N-benzyl-1-methyl-2-phenylsulfanyl-ethylamine

N-benzyl-N-[(S)-1-methyl-2-phenylsulfanylethyl]formamide