pyridine-2,6-dicarboxylic acid bis[3,5-bis(aminomethyl)-2,4,6-triethylbenzylamide]

Base Information

• Chemical Name: pyridine-2,6-dicarboxylic acid bis[3,5-bis(aminomethyl)-2,4,6-triethylbenzylamide]
• CAS No.: 854267-27-9
• Molecular Formula: C₃₇H₅₅N₇O₂
• Molecular Weight: 629.889
• Mol file: 854267-27-9.mol

Synonyms:pyridine-2,6-dicarboxylic acid bis[3,5-bis(aminomethyl)-2,4,6-triethylbenzylamide]

Chemical Property of pyridine-2,6-dicarboxylic acid bis[3,5-bis(aminomethyl)-2,4,6-triethylbenzylamide]

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of pyridine-2,6-dicarboxylic acid bis[3,5-bis(aminomethyl)-2,4,6-triethylbenzylamide]

There total 3 articles about pyridine-2,6-dicarboxylic acid bis[3,5-bis(aminomethyl)-2,4,6-triethylbenzylamide] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[3-[({6-[3,5-bis-(tert-butoxycarbonylamino-methyl)-2,4,6-triethyl-benzylcarbamoyl]-pyridine-2-carbonyl}-amino)-methyl]-5-(tert-butoxycarbonylamino-methyl)-2,4,6-triethyl-benzyl]-carbamic acid tert-butyl ester → pyridine-2,6-dicarboxylic acid bis[3,5-bis(aminomethyl)-2,4,6-triethylbenzylamide] (854267-27-9)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1002/chem.200400396

Reference yield:

2,6-Pyridinedicarbonyl dichloride (3739-94-4) → pyridine-2,6-dicarboxylic acid bis[3,5-bis(aminomethyl)-2,4,6-triethylbenzylamide] (854267-27-9)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N; K₂CO₃ / tetrahydrofuran

2: 3.9 g / trifluoroacetic acid / CH₂Cl₂ / 2 h / 20 °C

With potassium carbonate; triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;

DOI:10.1002/chem.200400396

Reference yield:

di-tert-butyl ((5-(aminomethyl)-2,4,6-triethyl-1,3-phenylene)bis(methylene)) dicarbamate (549507-66-6) → pyridine-2,6-dicarboxylic acid bis[3,5-bis(aminomethyl)-2,4,6-triethylbenzylamide] (854267-27-9)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N; K₂CO₃ / tetrahydrofuran

2: 3.9 g / trifluoroacetic acid / CH₂Cl₂ / 2 h / 20 °C

With potassium carbonate; triethylamine; trifluoroacetic acid; In tetrahydrofuran; dichloromethane;

DOI:10.1002/chem.200400396

upstream raw materials:

2,6-Pyridinedicarbonyl dichloride

di-tert-butyl ((5-(aminomethyl)-2,4,6-triethyl-1,3-phenylene)bis(methylene)) dicarbamate