549507-66-6Relevant articles and documents
Compounds Combining a Macrocyclic Building Block and Flexible Side-Arms as Carbohydrate Receptors: Syntheses and Structure-Binding Activity Relationship Studies
Amrhein, Felix,Mazik, Monika
, p. 6282 - 6303 (2021/09/18)
A series of new representatives of compounds combining a macrocyclic building block and flexible side-arms were prepared and their ability to act as carbohydrate receptors evaluated. The target compounds were obtained by multi-step syntheses, which included the preparation of numerous precursors as well as the isolation of a large number of by-products. The structure-binding activity relationship studies comprise, in particular, the variation of the side-arms in order to demonstrate the importance of the presence of a hydrogen bond donor in these units for the effective complexation of carbohydrates. Based on the findings of our previous studies, the variation of the bridge units is limited to benzene- and pyrrole-based moieties, whereby the use of the last-mentioned bridge type was expected to produce more effective systems. This assumption was confirmed by 1H NMR titrations and isothermal titration calorimetry.
Electroactive anion receptor with high affinity for arsenate
Etkind, Samuel I.,Vander Griend, Douglas A.,Swager, Timothy M.
supporting information, p. 10050 - 10061 (2020/10/02)
Herein, we present the synthesis and characterization of a macrocyclic polyamide cage that incorporates redox-active 1,4-dithiin units. UV/vis titration experiments with eight anions in acetonitrile revealed high affinity for H2AsO4
Synthesis and kinetic studies of a low-molecular weight organocatalyst for phosphate hydrolysis in water
Merschky, Michael,Schmuck, Carsten
experimental part, p. 4895 - 4903 (2010/02/16)
Kinetic studies of a low-molecular weight organocatalyst 1 are presented. Compound 1 contains two histidines and one cationic side chain attached to a central aromatic core. In aqueous solution 1 accelerates the hydrolysis of a prototypal phosphodiester w
A fluorescent sensor for 2,3-bisphosphoglycerate using a europium tetra-N-oxide bis-bipyridine complex for both binding and signaling purposes
Best, Michael D.,Anslyn, Eric V.
, p. 51 - 57 (2007/10/03)
Host 1 was designed and synthesized as a fluorescent sensor for 2,3-bisphosphoglycerate (BPG, 3). The design features a tris-functionalized triethylbenzene core to preorganize binding groups. The three cationic moieties, a tetra-N-oxide bipyridine-europiu
Metal triggered fluorescence sensing of citrate using a synthetic receptor
Cabell, Larry A.
, p. 315 - 323 (2007/10/03)
A metal containing fluorescent chemosensor was designed, synthesized, and studied for the quantification of citrate in common beverages. The sensor consists of Cu(II) bound by a 1,10-phenanthroline ligand which is attached to a bis(aminoimidazolium) recep