Technology Process of C33H33NO4*ClH
There total 6 articles about C33H33NO4*ClH which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
formic acid; C32H33NO4*ClH;
With
acetic acid;
In
water;
at 90 ℃;
With
hydrogenchloride;
In
methanol;
at -20 ℃;
DOI:10.1016/j.bmcl.2012.01.005
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: 180 °C / Neat (no solvent)
2.1: trichlorophosphate / benzene / 80 °C
3.1: [N-[(1R,2R)-2-(amino-κN)-1,2-diphenylethyl]-4-methylbenzenesulfonamidato-κN]chloro[(1,2, 3,4,5,6-η)-1-methyl-4-(1-methylethyl)benzene]-ruthenium; formic acid; triethylamine / N,N-dimethyl-formamide
4.1: hydrogenchloride / methanol; diethyl ether / -20 °C
5.1: acetic acid / water / 90 °C
5.2: -20 °C
With
hydrogenchloride; formic acid; [N-[(1R,2R)-2-(amino-κN)-1,2-diphenylethyl]-4-methylbenzenesulfonamidato-κN]chloro[(1,2, 3,4,5,6-η)-1-methyl-4-(1-methylethyl)benzene]-ruthenium; acetic acid; triethylamine; trichlorophosphate;
In
methanol; diethyl ether; water; N,N-dimethyl-formamide; benzene;
2.1: Bischler-Napieralski reaction / 5.1: Mannich reaction;
DOI:10.1016/j.bmcl.2012.01.005
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: trichlorophosphate / benzene / 80 °C
2.1: [N-[(1R,2R)-2-(amino-κN)-1,2-diphenylethyl]-4-methylbenzenesulfonamidato-κN]chloro[(1,2, 3,4,5,6-η)-1-methyl-4-(1-methylethyl)benzene]-ruthenium; formic acid; triethylamine / N,N-dimethyl-formamide
3.1: hydrogenchloride / methanol; diethyl ether / -20 °C
4.1: acetic acid / water / 90 °C
4.2: -20 °C
With
hydrogenchloride; formic acid; [N-[(1R,2R)-2-(amino-κN)-1,2-diphenylethyl]-4-methylbenzenesulfonamidato-κN]chloro[(1,2, 3,4,5,6-η)-1-methyl-4-(1-methylethyl)benzene]-ruthenium; acetic acid; triethylamine; trichlorophosphate;
In
methanol; diethyl ether; water; N,N-dimethyl-formamide; benzene;
1.1: Bischler-Napieralski reaction / 4.1: Mannich reaction;
DOI:10.1016/j.bmcl.2012.01.005
