ethyl dibromo(diphenylphosphono)acetate

Base Information

• Chemical Name: ethyl dibromo(diphenylphosphono)acetate
• CAS No.: 791130-78-4
• Molecular Formula: C₁₆H₁₅Br₂O₅P
• Molecular Weight: 478.074
• Mol file: 791130-78-4.mol

Synonyms:ethyl dibromo(diphenylphosphono)acetate

Chemical Property of ethyl dibromo(diphenylphosphono)acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of ethyl dibromo(diphenylphosphono)acetate

There total 1 articles about ethyl dibromo(diphenylphosphono)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diphenyl hydrogen phosphite (4712-55-4) → ethyl dibromo(diphenylphosphono)acetate (791130-78-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaH / tetrahydrofuran / 1 h / 0 °C

1.2: 86 percent / tetrahydrofuran / 12 h / 20 °C

2.1: NaH / tetrahydrofuran / 0.33 h / 20 °C

2.2: 87 percent / NBS / tetrahydrofuran / 0.5 h / 20 °C

With sodium hydride; In tetrahydrofuran;

DOI:10.1055/s-2004-831166

Reference yield: 54.0%

ethyl dibromo(diphenylphosphono)acetate (791130-78-4) → ethyl diphenylphosphonoacetate (16139-79-0) + ethyl bromo(diphenoxyphosphoryl)acetate (791130-77-3)

Guidance literature:

With tin(ll) chloride; In ethanol; at -40 ℃; for 0.166667h;

DOI:10.1055/s-2004-831166

Reference yield:

ethyl dibromo(diphenylphosphono)acetate (791130-78-4) → ethyl chloro(diphenylphosphono)acetate (791131-05-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 19 percent / SnCl₂*2H₂O / ethanol / 0.17 h / -40 °C

2.1: NaH / tetrahydrofuran / 0.17 h / 20 °C

2.2: 36 percent / N-chlorosuccinimide / tetrahydrofuran / 0.67 h / 20 °C

With sodium hydride; tin(ll) chloride; In tetrahydrofuran; ethanol;

DOI:10.1055/s-2004-831166

upstream raw materials:

diphenyl hydrogen phosphite

Downstream raw materials:

ethyl diphenylphosphonoacetate

ethyl bromo(diphenoxyphosphoryl)acetate

ethyl chloro(diphenylphosphono)acetate