(S)-methyl-2-acetamido-3-(3-formyl-4-methoxy-3-methylphenyl)propanoate

Base Information

• Chemical Name: (S)-methyl-2-acetamido-3-(3-formyl-4-methoxy-3-methylphenyl)propanoate
• CAS No.: 1177255-27-4
• Molecular Formula: C₁₅H₁₉NO₅
• Molecular Weight: 293.32
• Mol file: 1177255-27-4.mol

Synonyms:(S)-methyl-2-acetamido-3-(3-formyl-4-methoxy-3-methylphenyl)propanoate

Chemical Property of (S)-methyl-2-acetamido-3-(3-formyl-4-methoxy-3-methylphenyl)propanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-methyl-2-acetamido-3-(3-formyl-4-methoxy-3-methylphenyl)propanoate

There total 1 articles about (S)-methyl-2-acetamido-3-(3-formyl-4-methoxy-3-methylphenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

Dichloromethyl methyl ether (4885-02-3) + (S)-methyl-2-acetamido-3-(4-methoxy-3-methylphenyl)propanoate (1177255-26-3) → (S)-methyl-2-acetamido-3-(3-formyl-4-methoxy-3-methylphenyl)propanoate (1177255-27-4)

Guidance literature:

With titanium tetrachloride; In dichloromethane; at 0 ℃; for 4h;

DOI:10.1016/j.tet.2009.05.025

Reference yield: 91.0%

(S)-methyl-2-acetamido-3-(3-formyl-4-methoxy-3-methylphenyl)propanoate (1177255-27-4) → (S)-methyl-2-acetamido-3-(3-hydroxy-4-methoxy-5-methylphenyl)propanoate (1177255-28-5)

Guidance literature:

(S)-methyl-2-acetamido-3-(3-formyl-4-methoxy-3-methylphenyl)propanoate; With 3-chloro-benzenecarboperoxoic acid; In chloroform; at 20 ℃; for 6h;

With hydrogenchloride; In methanol; water; at 0 - 20 ℃;

DOI:10.1016/j.tet.2009.05.025

Reference yield:

(S)-methyl-2-acetamido-3-(3-formyl-4-methoxy-3-methylphenyl)propanoate (1177255-27-4) → C15H19NO6

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In chloroform; at 20 ℃; for 6h;

DOI:10.1002/jhet.609

upstream raw materials:

Dichloromethyl methyl ether

(S)-methyl-2-acetamido-3-(4-methoxy-3-methylphenyl)propanoate

Downstream raw materials:

(S)-methyl-2-acetamido-3-(3-hydroxy-4-methoxy-5-methylphenyl)propanoate

(-)-MY 336a

C₁₃H₁₉NO₄

(1R,3S)-1-(benzyloxymethyl)-3-(hydroxyl-methyl)-7-methoxy-6-methyl-1,2,3,4-tetra-hydroisoquinolin-8-ol