C₄₂H₄₈N₂O₈S₂Si

Base Information

• Chemical Name: C₄₂H₄₈N₂O₈S₂Si
• CAS No.: 221526-59-6
• Molecular Formula: C₄₂H₄₈N₂O₈S₂Si
• Molecular Weight: 801.069
• Mol file: 221526-59-6.mol

Synonyms:C₄₂H₄₈N₂O₈S₂Si

Chemical Property of C₄₂H₄₈N₂O₈S₂Si

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₂H₄₈N₂O₈S₂Si

There total 16 articles about C₄₂H₄₈N₂O₈S₂Si which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-Benzenesulfonyl-3,4,5,6-tetrahydropyridin-2-one (7744-25-4) → C42H48N2O8S2Si (221526-59-6)

Guidance literature:

Multi-step reaction with 11 steps

1: 73 percent / LiN(TMS)2 / tetrahydrofuran / 11 h / -60 °C

2: LiN(TMS)2 / tetrahydrofuran / 2 h / -60 °C

3: n-Bu₃SnH, AIBN / benzene / 0.5 h / Heating

4: KN(TMS)2 / tetrahydrofuran / -30 °C

5: mCPBA / CH₂Cl₂

6: various solvent(s) / 20 h / 180 °C

7: PPTS / CH₂Cl₂

8: 21 percent / HCl / tetrahydrofuran / 2 h / Heating

9: HCl

10: imidazole / dimethylformamide / 2 h / Ambient temperature

11: p-TsOH / benzene / 2 h / Heating

With 1H-imidazole; hydrogenchloride; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; pyridinium p-toluenesulfonate; potassium hexamethylsilazane; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; benzene;

DOI:10.1016/S0040-4039(98)80033-6

Reference yield:

(RS)-1-benzenesulfonyl-3-[(4R)-3-benzenesulfonyl-2,2-dimethyloxazolidin-4-ylmethyl]-piperidin-2-one (221526-73-4) → C42H48N2O8S2Si (221526-59-6)

Guidance literature:

Multi-step reaction with 8 steps

1: KN(TMS)2 / tetrahydrofuran / -30 °C

2: mCPBA / CH₂Cl₂

3: various solvent(s) / 20 h / 180 °C

4: PPTS / CH₂Cl₂

5: 21 percent / HCl / tetrahydrofuran / 2 h / Heating

6: HCl

7: imidazole / dimethylformamide / 2 h / Ambient temperature

8: p-TsOH / benzene / 2 h / Heating

With 1H-imidazole; hydrogenchloride; pyridinium p-toluenesulfonate; potassium hexamethylsilazane; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; benzene;

DOI:10.1016/S0040-4039(98)80033-6

Reference yield:

methyl N-benzenesulfonyl-L-serinate (221526-66-5) → C42H48N2O8S2Si (221526-59-6)

Guidance literature:

Multi-step reaction with 13 steps

1: 90 percent / p-TsOH / benzene / 3 h / Ambient temperature

2: 92 percent / DIBAL-H / toluene / 2 h / -78 °C

3: 73 percent / LiN(TMS)2 / tetrahydrofuran / 11 h / -60 °C

4: LiN(TMS)2 / tetrahydrofuran / 2 h / -60 °C

5: n-Bu₃SnH, AIBN / benzene / 0.5 h / Heating

6: KN(TMS)2 / tetrahydrofuran / -30 °C

7: mCPBA / CH₂Cl₂

8: various solvent(s) / 20 h / 180 °C

9: PPTS / CH₂Cl₂

10: 21 percent / HCl / tetrahydrofuran / 2 h / Heating

11: HCl

12: imidazole / dimethylformamide / 2 h / Ambient temperature

13: p-TsOH / benzene / 2 h / Heating

With 1H-imidazole; hydrogenchloride; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; pyridinium p-toluenesulfonate; potassium hexamethylsilazane; diisobutylaluminium hydride; toluene-4-sulfonic acid; 3-chloro-benzenecarboperoxoic acid; lithium hexamethyldisilazane; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene; benzene;

DOI:10.1016/S0040-4039(98)80033-6

upstream raw materials:

ethylene glycol

3,9-bis-benzenesulfonyl-2-(tert-butyl-diphenyl-silanyloxymethyl)-octahydro-3,9-diaza-cyclopenta[d]naphthalene-5,10-dione

1-Benzenesulfonyl-3,4,5,6-tetrahydropyridin-2-one

tert-butylchlorodiphenylsilane

Downstream raw materials:

C₃₅H₄₈N₂O₆Si

C₃₆H₄₄N₂O₆SSi