2-ETHYL-4-METHYLPENTANENITRILE

Base Information

• Chemical Name: 2-ETHYL-4-METHYLPENTANENITRILE
• CAS No.: 79509-80-1
• Molecular Formula: C7H13 N
• Molecular Weight: 111.187
• Mol file: 79509-80-1.mol

Synonyms:Valeronitrile,2-ethyl- (6CI); 2-Ethylpentanenitrile

Chemical Property of 2-ETHYL-4-METHYLPENTANENITRILE

Chemical Property:

• PSA: 23.79000
• LogP: 2.58228

Purity/Quality:

99%min ^*data from raw suppliers

2-ETHYL-4-METHYLPENTANENITRILE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-ETHYL-4-METHYLPENTANENITRILE

There total 1 articles about 2-ETHYL-4-METHYLPENTANENITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hexane (110-54-3) + P-toluenesulfonyl cyanide (19158-51-1) → heptanenitrile (629-08-3) + 2-methylhexanonitrile (20654-42-6) + ethyl-2-butyl-carbonitrile (79509-80-1)

Guidance literature:

With tetrakis(tetrabutylammonium)decatungstate(VI); In water; acetonitrile; for 5h; Overall yield = 59 percent; Overall yield = 13.2 mg; Irradiation; Inert atmosphere;

DOI:10.1021/acs.orglett.1c01846

Reference yield:

ethyl-2-butyl-carbonitrile (79509-80-1) → N-(2-ethylpentyl)-4-methylbenzenesulfonamide

Guidance literature:

Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 24 h / 70 °C

2: triethylamine / dichloromethane / 24 h / 0 - 20 °C

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1039/c7cc02624b

Reference yield:

ethyl-2-butyl-carbonitrile (79509-80-1) → 4-ethyl-2-methyl-1-tosylpyrrolidine

Guidance literature:

Multi-step reaction with 3 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / 24 h / 70 °C

2: triethylamine / dichloromethane / 24 h / 0 - 20 °C

3: bis-[(trifluoroacetoxy)iodo]benzene; copper(l) iodide / 1,2-dichloro-ethane / 10 h / 100 °C

With copper(l) iodide; lithium aluminium tetrahydride; triethylamine; bis-[(trifluoroacetoxy)iodo]benzene; In tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane;

DOI:10.1039/c7cc02624b

upstream raw materials:

hexane

P-toluenesulfonyl cyanide

Refernces