20654-42-6

Basic information

• Product Name: 2-METHYLHEXANENITRILE
• Synonyms: 2-cyanohexane;2-METHYLHEXANENITRILE
• CAS NO: 20654-42-6
• Molecular Formula: C₇H₁₃N
• Molecular Weight: 111.18
• Mol File: 20654-42-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-METHYLHEXANENITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYLHEXANENITRILE(20654-42-6)
• EPA Substance Registry System: 2-METHYLHEXANENITRILE(20654-42-6)

Safety Data

• Hazardous Substances Data: 20654-42-6(Hazardous Substances Data)

Upstream product

• 110-54-3 hexane 
• 19158-51-1 P-toluenesulfonyl cyanide 
• 592-41-6 1-hexene 
• 75-86-5 2-hydroxy-2-methylpropanenitrile 

Downstream Products

• 44652-67-7 (+/-)-1-amino-2-methylhexane 

Relevant articles and documents

Direct C(sp3)-H Cyanation Enabled by a Highly Active Decatungstate Photocatalyst

A highly efficient, direct C(sp3)-H cyanation was developed under mild photocatalytic conditions. The method enabled the direct cyanation of various C(sp3)-H substrates with excellent functional group tolerance. Notably, complex natural products and bioactive compounds were efficiently cyanated.

Efficient nickel-catalyzed hydrocyanation of alkenes using acetone cyanohydrin as a safer cyano source

An active nickel catalyst prepared in situ from a Ni(II) compound, phosphine ligand, and zinc powder was found to be an efficient catalyst system for the hydrocyanation of various alkenes using acetone cyanohydrin as a safer cyano source. The combination of NiCl2·6H2O and 1,3-bis(diphenylphosphino)propane was the most efficient catalyst precursor in DMF. Under the optimized conditions, various styrenes, heterocyclic alkenes, and aliphatic alkenes were converted to their corresponding nitriles in excellent yields.