C₁₇H₁₃FO

Base Information

• Chemical Name: C₁₇H₁₃FO
• CAS No.: 368842-45-9
• Molecular Formula: C₁₇H₁₃FO
• Molecular Weight: 252.288
• Mol file: 368842-45-9.mol

Synonyms:C₁₇H₁₃FO

Chemical Property of C₁₇H₁₃FO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₇H₁₃FO

There total 2 articles about C₁₇H₁₃FO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(4-fluorophenyl)but-3-en-2-one (65300-29-0,1611-38-7) + benzaldehyde (100-52-7) → C17H13FO (368842-45-9)

Guidance literature:

With sodium hydroxide; In ethanol; at 20 ℃;

DOI:10.1039/c3ob41400k

Reference yield:

4-fluorobenzaldehyde (459-57-4) → C17H13FO (368842-45-9)

Guidance literature:

Multi-step reaction with 2 steps

1: calcium hydroxide / ethanol; water / 10 h / 50 °C / Inert atmosphere; Green chemistry

2: calcium hydroxide / ethanol; water / 48 h / 80 °C / Inert atmosphere; Green chemistry

With calcium hydroxide; In ethanol; water; 1: |Claisen-Schmidt Condensation / 2: |Claisen-Schmidt Condensation;

DOI:10.1016/j.cclet.2018.01.035

Reference yield: 89.0%

C17H13FO (368842-45-9) + (trifluoromethyl)trimethylsilane (81290-20-2) → C21H22F4OSi

Guidance literature:

With sodium acetate; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h; regioselective reaction;

DOI:10.1039/c3ob41400k

upstream raw materials:

4-(4-fluorophenyl)but-3-en-2-one

benzaldehyde

4-fluorobenzaldehyde

Downstream raw materials:

1-fluoro-4-(2-phenyl-4-(trifluoromethyl)cyclopenta-1,3-dien-1-yl)benzene

1-fluoro-4-(2-phenyl-4-(trifluoromethyl)cyclopenta-1,4-dien-1-yl)benzene

(Z)-3-((dimethylamino)methylene)-5-(4-fluorophenyl)-4-phenyl-2-(trifluoromethyl)cyclopenta-1,4-dienecarbaldehyde

(Z)-3-((dimethylamino)methylene)-4-(4-fluorophenyl)-5-phenyl-2-(trifluoromethyl)cyclopenta-1,4-dienecarbaldehyde