2-cyano-N-(4-sulfamoylphenyl)-3,3-bis(methylsulfanyl)acrylamide

Base Information

• Chemical Name: 2-cyano-N-(4-sulfamoylphenyl)-3,3-bis(methylsulfanyl)acrylamide
• CAS No.: 1224956-98-2
• Molecular Formula: C₁₂H₁₃N₃O₃S₃
• Molecular Weight: 343.452
• Mol file: 1224956-98-2.mol

Synonyms:2-cyano-N-(4-sulfamoylphenyl)-3,3-bis(methylsulfanyl)acrylamide

Chemical Property of 2-cyano-N-(4-sulfamoylphenyl)-3,3-bis(methylsulfanyl)acrylamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2-cyano-N-(4-sulfamoylphenyl)-3,3-bis(methylsulfanyl)acrylamide

There total 1 articles about 2-cyano-N-(4-sulfamoylphenyl)-3,3-bis(methylsulfanyl)acrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

carbon disulfide (75-15-0,12122-00-8) + N-[4-(aminosulfonyl)phenyl]-2-cyanoacetamide (32933-40-7) + dimethyl sulfate (77-78-1) → 2-cyano-N-(4-sulfamoylphenyl)-3,3-bis(methylsulfanyl)acrylamide (1224956-98-2)

Guidance literature:

carbon disulfide; N-[4-(aminosulfonyl)phenyl]-2-cyanoacetamide; With potassium hydroxide; In N,N-dimethyl-formamide; at 0 - 20 ℃;

dimethyl sulfate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 6h;

DOI:10.1002/jccs.200900154

Reference yield: 60.0%

2-cyano-N-(4-sulfamoylphenyl)-3,3-bis(methylsulfanyl)acrylamide (1224956-98-2) → 5-amino-3-methylsulfanyl-4-(4-sulfamoylphenyl)carbamoylpyrazole (1224956-99-3)

Guidance literature:

With hydrazine; In ethanol; for 24h; Reflux;

DOI:10.1002/jccs.200900154

upstream raw materials:

carbon disulfide

N-[4-(aminosulfonyl)phenyl]-2-cyanoacetamide

dimethyl sulfate

Downstream raw materials:

5-amino-3-methylsulfanyl-4-(4-sulfamoylphenyl)carbamoylpyrazole