N-[(1S,2R)-1-Benzyl-2-hydroxy-3-(3-trifluoromethyl-benzylamino)-propyl]-iso phthalamic acid methyl ester

Base Information

Chemical Name:N-[(1S,2R)-1-Benzyl-2-hydroxy-3-(3-trifluoromethyl-benzylamino)-propyl]-iso phthalamic acid methyl ester
CAS No.:1361325-39-4
Molecular Formula:C₂₇H₂₇F₃N₂O₄
Molecular Weight:500.518
Hs Code.:

Synonyms:N-[(1S,2R)-1-Benzyl-2-hydroxy-3-(3-trifluoromethyl-benzylamino)-propyl]-iso phthalamic acid methyl ester

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Chemical Property of N-[(1S,2R)-1-Benzyl-2-hydroxy-3-(3-trifluoromethyl-benzylamino)-propyl]-iso phthalamic acid methyl ester

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Technology Process of N-[(1S,2R)-1-Benzyl-2-hydroxy-3-(3-trifluoromethyl-benzylamino)-propyl]-iso phthalamic acid methyl ester

There total 1 articles about N-[(1S,2R)-1-Benzyl-2-hydroxy-3-(3-trifluoromethyl-benzylamino)-propyl]-iso phthalamic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (2R,3S)-3-amino-4-phenyl-1-{[3-(trifluoromethyl)benzyl]amino}butan-2-ol di-hydrochloride

: 1877-71-0
benzene 1,3-dicarboxylic acid monomethyl ester

: 1361325-39-4
N-[(1S,2R)-1-Benzyl-2-hydroxy-3-(3-trifluoromethyl-benzylamino)-propyl]-iso phthalamic acid methyl ester

Guidance literature:: benzene 1,3-dicarboxylic acid monomethyl ester; With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; In N,N-dimethyl-formamide; at 22 ℃; for 0.5h;

(2R,3S)-3-amino-4-phenyl-1-{[3-(trifluoromethyl)benzyl]amino}butan-2-ol di-hydrochloride; With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 22 ℃; for 5h;