Technology Process of C17H16N4
There total 5 articles about C17H16N4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
potassium cyanide; (Z)-2-{3-chloro-3-[4-(diethylamino)phenyl]allylidene}malononitrile;
With
tetrakis(triphenylphosphine) palladium(0); 18-crown-6 ether;
In
toluene;
at 95 ℃;
for 1.5h;
With
copper(l) cyanide;
In
N,N-dimethyl-formamide; toluene;
at 95 ℃;
DOI:10.1002/ejoc.201200111
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: acetonitrile / 2 h / 90 °C
2.1: tetrakis(triphenylphosphine) palladium(0); 18-crown-6 ether / toluene / 1.5 h / 95 °C
2.2: 95 °C
With
tetrakis(triphenylphosphine) palladium(0); 18-crown-6 ether;
In
toluene; acetonitrile;
DOI:10.1002/ejoc.201200111
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium carbonate / N,N-dimethyl-formamide / 14 h / 70 °C
2.1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; diisopropylamine / 14 h / 20 °C / Inert atmosphere
3.1: potassium carbonate / methanol / 2 h / 20 °C
4.1: acetonitrile / 2 h / 90 °C
5.1: tetrakis(triphenylphosphine) palladium(0); 18-crown-6 ether / toluene / 1.5 h / 95 °C
5.2: 95 °C
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); 18-crown-6 ether; sodium carbonate; potassium carbonate; diisopropylamine;
In
methanol; N,N-dimethyl-formamide; toluene; acetonitrile;
DOI:10.1002/ejoc.201200111
