5,6-bis[3,5-di(tert-butyl)-4-hydroxyphenyl]pyrazine-2,3-dicarbonitrile

Base Information

• Chemical Name: 5,6-bis[3,5-di(tert-butyl)-4-hydroxyphenyl]pyrazine-2,3-dicarbonitrile
• CAS No.: 1373213-10-5
• Molecular Formula: C₃₄H₄₂N₄O₂
• Molecular Weight: 538.733
• Mol file: 1373213-10-5.mol

Synonyms:5,6-bis[3,5-di(tert-butyl)-4-hydroxyphenyl]pyrazine-2,3-dicarbonitrile

Chemical Property of 5,6-bis[3,5-di(tert-butyl)-4-hydroxyphenyl]pyrazine-2,3-dicarbonitrile

Chemical Property:

Purity/Quality:

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Technology Process of 5,6-bis[3,5-di(tert-butyl)-4-hydroxyphenyl]pyrazine-2,3-dicarbonitrile

There total 1 articles about 5,6-bis[3,5-di(tert-butyl)-4-hydroxyphenyl]pyrazine-2,3-dicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

2,6-di-tert-butylphenol (128-39-2) + 2,3-dichloro-5,6-dicyanopyrazine (56413-95-7) → 5,6-bis[3,5-di(tert-butyl)-4-hydroxyphenyl]pyrazine-2,3-dicarbonitrile (1373213-10-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 6h;

DOI:10.1039/c2cc30712j

Reference yield: 71.0%

5,6-bis[3,5-di(tert-butyl)-4-hydroxyphenyl]pyrazine-2,3-dicarbonitrile (1373213-10-5) + magnesium di-n-butanolate (15921-15-0) → 2,3,9,10,16,17,23,24-octakis[3,5-di(tert-butyl)-4-hydroxyphenyl]-1,4,8,11,15,18,22,25-octaazaphthalocyaninato magnesium(II)

Guidance literature:

In butan-1-ol; for 19h; Reflux;

DOI:10.1002/chem.201502533

Reference yield: 21.0%

5,6-bis((tert-butyl)sulfanyl)pyrazine-2,3-dicarbonitrile (927874-88-2) + 5,6-bis[3,5-di(tert-butyl)-4-hydroxyphenyl]pyrazine-2,3-dicarbonitrile (1373213-10-5) → 2,3-bis[3,5-di(tert-butyl)-4-hydroxyphenyl]-9,10,16,17,23,24-hexakis(tert-butylsulfanyl)-1,4,8,11,15,18,22,25-octaazaphthalocyanine + 2,3,9,10-tetrakis[3,5-di(tert-butyl)-4-hydroxyphenyl]-16,17,23,24-tetrakis(tert-butylsulfanyl)-1,4,8,11,15,18,22,25-octaazaphthalocyanine

Guidance literature:

5,6-bis((tert-butyl)sulfanyl)pyrazine-2,3-dicarbonitrile; 5,6-bis[3,5-di(tert-butyl)-4-hydroxyphenyl]pyrazine-2,3-dicarbonitrile; With magnesium di-n-butanolate; In butan-1-ol; for 6h; Reflux;

With toluene-4-sulfonic acid; In tetrahydrofuran; at 20 ℃; for 4h;

DOI:10.1002/chem.201502533

upstream raw materials:

2,6-di-tert-butylphenol

2,3-dichloro-5,6-dicyanopyrazine

Downstream raw materials:

2,3,9,10,16,17,23,24-octakis[3,5-di (tert-butyl)-4-hydroxyphenyl]-1,4,8,11,15,18,22,25-octaazaphthalocyanine