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2-(N-phenyl carboxamidomethyl thio)-5-phenyl-1,3,4-oxadiazole

Base Information Edit
  • Chemical Name:2-(N-phenyl carboxamidomethyl thio)-5-phenyl-1,3,4-oxadiazole
  • CAS No.:81511-63-9
  • Molecular Formula:C16H13N3O2S
  • Molecular Weight:311.364
  • Hs Code.:
  • Mol file:81511-63-9.mol
2-(N-phenyl carboxamidomethyl thio)-5-phenyl-1,3,4-oxadiazole

Synonyms:2-(N-phenyl carboxamidomethyl thio)-5-phenyl-1,3,4-oxadiazole

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Chemical Property of 2-(N-phenyl carboxamidomethyl thio)-5-phenyl-1,3,4-oxadiazole Edit
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Technology Process of 2-(N-phenyl carboxamidomethyl thio)-5-phenyl-1,3,4-oxadiazole

There total 5 articles about 2-(N-phenyl carboxamidomethyl thio)-5-phenyl-1,3,4-oxadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
2-Mercapto-5-phenyl-1,3,4-oxadiazole; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;
N-chloroacetyl-aniline; In N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2021.116222
Guidance literature:
Multi-step reaction with 3 steps
1.1: hydrazine hydrate monohydrate / ethanol / Reflux
2.1: potassium hydroxide / ethanol / 0.17 h / Inert atmosphere
2.2: Reflux
2.3: 70 - 80 °C
3.1: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere
3.2: 20 °C / Inert atmosphere
With potassium carbonate; hydrazine hydrate monohydrate; potassium hydroxide; In ethanol; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2021.116222
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