C₂₃H₂₉ClOSi

Base Information

Chemical Name:C₂₃H₂₉ClOSi
CAS No.:1191268-97-9
Molecular Formula:C₂₃H₂₉ClOSi
Molecular Weight:385.021
Hs Code.:

Synonyms:C₂₃H₂₉ClOSi

Suppliers and Price of C₂₃H₂₉ClOSi

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,1''-[[[(4R)-4-Chloro-6-heptyn-1-yl]oxy](1,1-dimethylethyl)silylene]bis[benzene]
10mg
$ 1320.00

Total 1 raw suppliers

Chemical Property of C₂₃H₂₉ClOSi

Chemical Property:

Boiling Point:440.5±45.0 °C(Predicted)
Density:1.04±0.1 g/cm3(Predicted)

Purity/Quality:

97%,98%,99% ^*data from raw suppliers

1,1''-[[[(4R)-4-Chloro-6-heptyn-1-yl]oxy](1,1-dimethylethyl)silylene]bis[benzene] ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 1,1''-[[[(4R)-4-Chloro-6-heptyn-1-yl]oxy](1,1-dimethylethyl)silylene]bis[benzene], is an intermediate in the synthesis of Eribulin (E615203).

Technology Process of C₂₃H₂₉ClOSi

There total 9 articles about C₂₃H₂₉ClOSi which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 606942-43-2
(S)-7-((tert-butyldiphenylsilyl)oxy)hept-1-yn-4-ol

: 1191268-97-9
C₂₃H₂₉ClOSi

Guidance literature:: With pyridine; trichloroacetamide; triphenylphosphine; In dichloromethane; at 20 ℃; for 24h; Inert atmosphere;
DOI:10.1021/ol9016595

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 1191268-97-9
C₂₃H₂₉ClOSi

Guidance literature:: Multi-step reaction with 6 steps

1: 1H-imidazole; dmap / N,N-dimethyl-formamide / 12 h / 0 °C / Inert atmosphere

2: ozone / dichloromethane / -78 °C

3: ammonium chloride; zinc / tetrahydrofuran / -15 °C

4: Amano Lipase PS / tert-butyl methyl ether / 24 h / 27 °C / Enzymatic reaction

5: potassium carbonate; methanol

6: trichloroacetamide; triphenylphosphine; pyridine / dichloromethane / 24 h / 27 °C

With pyridine; 1H-imidazole; methanol; dmap; Amano Lipase PS; trichloroacetamide; potassium carbonate; ammonium chloride; ozone; triphenylphosphine; zinc; In tetrahydrofuran; dichloromethane; tert-butyl methyl ether; N,N-dimethyl-formamide;
DOI:10.1021/acs.oprd.0c00308

Reference yield:

: 132047-92-8
tert-butyl(pent-4-en-1-yloxy)diphenylsilane

: 1191268-97-9
C₂₃H₂₉ClOSi

Guidance literature:: Multi-step reaction with 5 steps

1: ozone / dichloromethane / -78 °C

2: ammonium chloride; zinc / tetrahydrofuran / -15 °C

3: Amano Lipase PS / tert-butyl methyl ether / 24 h / 27 °C / Enzymatic reaction

4: potassium carbonate; methanol

5: trichloroacetamide; triphenylphosphine; pyridine / dichloromethane / 24 h / 27 °C

With pyridine; methanol; Amano Lipase PS; trichloroacetamide; potassium carbonate; ammonium chloride; ozone; triphenylphosphine; zinc; In tetrahydrofuran; dichloromethane; tert-butyl methyl ether;
DOI:10.1021/acs.oprd.0c00308