4-(Tert-butyldiphenylsilyloxy)butanal

Base Information

• Chemical Name: 4-(Tert-butyldiphenylsilyloxy)butanal
• CAS No.: 127793-62-8
• Molecular Formula: C20H26O2Si
• Molecular Weight: 326.511
• DSSTox Substance ID: DTXSID90446615
• Nikkaji Number: J1.276.241K
• Wikidata: Q82265328
• Mol file: 127793-62-8.mol

Synonyms:127793-62-8;4-(tert-butyldiphenylsilyloxy)butanal;Butanal, 4-[[(1,1-dimethylethyl)diphenylsilyl]oxy]-;4-[tert-butyl(diphenyl)silyl]oxybutanal;4-{[tert-butyl(diphenyl)silyl]oxy)butanal;4-{[tert-butyl(diphenyl)silyl]oxy}butanal;SCHEMBL641418;DTXSID90446615;FIGNMIFTOBCQOY-UHFFFAOYSA-N;4-(t-butyldiphenylsilyloxy)butanal;4-(tert-Butyldiphenylsiloxy)butanal;4-(tert-butyidiphenylsilyloxy)butanal;FT-0749925;4-(tert-Butyl-diphenyl-silanyloxy)-butyraldehyde;A934917

Chemical Property of 4-(Tert-butyldiphenylsilyloxy)butanal

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 8
• Exact Mass: 326.170206602
• Heavy Atom Count: 23
• Complexity: 331

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(C)(C)[Si](C1=CC=CC=C1)(C2=CC=CC=C2)OCCCC=O

Technology Process of 4-(Tert-butyldiphenylsilyloxy)butanal

There total 16 articles about 4-(Tert-butyldiphenylsilyloxy)butanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-(tret-butyldiphenylsilyloxy)butan-1-ol (130372-07-5) → 4-((tert-butyldiphenylsilyl)oxy)butanal (127793-62-8)

Guidance literature:

With N-methyl-2-indolinone; tetrapropylammonium perruthennate; In dichloromethane; acetonitrile; at 20 ℃;

DOI:10.1016/j.bmcl.2006.10.060

Reference yield: 96.0%

Butane-1,4-diol (110-63-4) + tert-butylchlorodiphenylsilane (58479-61-1) → 4-((tert-butyldiphenylsilyl)oxy)butanal (127793-62-8)

Guidance literature:

Butane-1,4-diol; tert-butylchlorodiphenylsilane; With sodium hydride; In tetrahydrofuran;

With pyridine-SO₃ complex; triethylamine; In dimethyl sulfoxide; Further stages.;

DOI:10.1016/j.tetlet.2007.06.058

Reference yield: 92.0%

2-[3-(tert-butyldiphenylsilyloxy)propyl]-1,3-dithiane (468097-84-9) → 4-((tert-butyldiphenylsilyl)oxy)butanal (127793-62-8)

Guidance literature:

With calcium carbonate; methyl iodide; In water; acetonitrile; at 20 ℃;

DOI:10.1016/S0040-4039(02)01129-2

upstream raw materials:

4-(tret-butyldiphenylsilyloxy)butan-1-ol

tert-butyl(pent-4-en-1-yloxy)diphenylsilane

3-tert.butyldiphenylsilyloxy-propionitrile

Butane-1,4-diol

Downstream raw materials:

5-hydroxy-3-oxo-7-t.butyldiphenylsilyloxy-heptanoic acid methyl ester

5-hydroxy-3-oxo-7-t.butyldiphenylsilyloxy-heptanoic acid benzyl ester

5-hydroxy-3-oxo-7-t.butyldiphenylsilyloxy-heptanoic acid t.butyl ester

6-(tert-Butyl-diphenyl-silanyloxy)-1-phenyl-hex-1-yn-3-ol