2-(4-Bromo-3-methylphenyl)ethanamine

Base Information

Chemical Name:2-(4-Bromo-3-methylphenyl)ethanamine
CAS No.:786625-94-3
Molecular Formula:C₉H₁₂BrN
Molecular Weight:214.105
Hs Code.:
DSSTox Substance ID:DTXSID20593560
Wikidata:Q82488061
Mol file:786625-94-3.mol

Synonyms:2-(4-Bromo-3-methylphenyl)ethanamine;786625-94-3;2-(4-Bromo-3-methylphenyl)ethan-1-amine;Benzeneethanamine,4-bromo-3-methyl-;SCHEMBL5524133;DTXSID20593560;AB8409;MFCD14582923;AKOS015150917;DA-02781;Benzeneethanamine, 4-bromo-3-methyl- (9CI);EN300-1893766;A1-18927

Suppliers and Price of 2-(4-Bromo-3-methylphenyl)ethanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

A1 Biochem Labs
2-(4-Bromo-3-methylphenyl)ethan-1-amine 95%
2.5 g
$ 1200.00

Total 4 raw suppliers

Chemical Property of 2-(4-Bromo-3-methylphenyl)ethanamine

Chemical Property:

PSA：26.02000
LogP:2.95900
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:213.01531
Heavy Atom Count:11
Complexity:116

Purity/Quality:

99% ^*data from raw suppliers

2-(4-Bromo-3-methylphenyl)ethan-1-amine 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=CC(=C1)CCN)Br

Technology Process of 2-(4-Bromo-3-methylphenyl)ethanamine

There total 4 articles about 2-(4-Bromo-3-methylphenyl)ethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 215800-25-2
2-(4-bromo-3-methyl-phenyl)acetonitrile

: 786625-94-3
C₉H₁₂BrN

Guidance literature:: With borane-THF; In tetrahydrofuran; at 0 ℃; for 22h; Reflux;
DOI:10.1021/acs.jmedchem.7b00835

Reference yield:

: 27561-51-9
1-bromo-4-(bromomethyl)-2-methylbenzene

: 786625-94-3
C₉H₁₂BrN

Guidance literature:: Multi-step reaction with 2 steps

1: tetrabutylammomium bromide / water; dichloromethane / 20 °C

2: borane-THF / tetrahydrofuran / 22 h / 0 °C / Reflux

With borane-THF; tetrabutylammomium bromide; In tetrahydrofuran; dichloromethane; water;
DOI:10.1021/acs.jmedchem.7b00835

Reference yield:

: 148547-19-7
4-Bromo-3-methylbenzoic acid methyl ester

: 786625-94-3
C₉H₁₂BrN

Guidance literature:: Multi-step reaction with 4 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / -15 °C

2: triphenylphosphine; carbon tetrabromide / dichloromethane / 0 °C

3: tetrabutylammomium bromide / water; dichloromethane / 20 °C

4: borane-THF / tetrahydrofuran / 22 h / 0 °C / Reflux

With lithium aluminium tetrahydride; borane-THF; carbon tetrabromide; tetrabutylammomium bromide; triphenylphosphine; In tetrahydrofuran; dichloromethane; water;
DOI:10.1021/acs.jmedchem.7b00835