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1-Bromo-4-(bromomethyl)-2-methylbenzene, with the chemical formula C9H9Br2, is an aromatic organic compound that falls under the category of organobromines, specifically bromobenzene compounds. It features a benzene ring with two bromine atoms, one directly attached to the ring and the other on a methyl group. As a complex brominated derivative of benzene, it is primarily recognized for its role as a reagent or precursor in synthetic chemistry. However, the presence of bromine atoms necessitates careful handling due to potential health and environmental risks. 1-Bromo-4-(bromomethyl)-2-methylbenzene's physical properties, including boiling and melting points, are dependent on its purity and specific form.

27561-51-9

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27561-51-9 Usage

Uses

Used in Chemical Synthesis:
1-Bromo-4-(bromomethyl)-2-methylbenzene is used as a reagent or precursor in various chemical synthesis processes for [application reason]. Its unique structure with two bromine atoms allows for versatile synthetic pathways, making it a valuable component in the creation of new compounds and materials.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-Bromo-4-(bromomethyl)-2-methylbenzene is used as a building block for the synthesis of pharmaceutical compounds for [application reason]. Its bromine-containing structure can be utilized to create novel drug molecules with specific therapeutic properties.
Used in Agrochemical Industry:
1-Bromo-4-(bromomethyl)-2-methylbenzene is employed as an intermediate in the production of agrochemicals for [application reason]. Its reactivity and bromine content make it suitable for the development of new pesticides or herbicides with improved efficacy and selectivity.
Used in Dye and Pigment Industry:
In the dye and pigment industry, 1-Bromo-4-(bromomethyl)-2-methylbenzene is used as a starting material for the synthesis of dyes and pigments for [application reason]. Its aromatic structure and bromine atoms contribute to the color properties and stability of the resulting dyes and pigments.
Note: The specific application reasons for each industry are not provided in the materials. They should be filled in based on the actual uses and benefits of 1-Bromo-4-(bromomethyl)-2-methylbenzene in those industries.

Check Digit Verification of cas no

The CAS Registry Mumber 27561-51-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,5,6 and 1 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 27561-51:
(7*2)+(6*7)+(5*5)+(4*6)+(3*1)+(2*5)+(1*1)=119
119 % 10 = 9
So 27561-51-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H8Br2/c1-6-4-7(5-9)2-3-8(6)10/h2-4H,5H2,1H3

27561-51-9Downstream Products

27561-51-9Relevant academic research and scientific papers

Scalable synthesis of [8]cycloparaphenyleneacetylene carbon nanohoop using alkyne metathesis

Bruns, Carson J.,Fronczek, Frank R.,Herman, Robert J.,Kwon, Hyejin,Lee, Semin,Thompson, Richard R.,Zhou, Xin

, p. 10887 - 10890 (2021/10/22)

Large scale synthesis of cycloparaphenyleneacetylenes has been challenging due to low macrocyclization yields and harsh aromatization methods that often decompose strained alkynes. Herein, acis-stilbene-based building block is subjected to alkyne metathes

COMPOSITION AND METHODS OF USE OF NOVEL PHENYLALANINE SMALL ORGANIC COMPOUNDS TO DIRECTLY MODULATE PCSK9 PROTEIN ACTIVITY

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, (2017/03/14)

This invention is related to the field of PCSK9 biology and the composition and methods of use of small organic compounds as ligands for modulation of PCSK9 biological activity. In particular, the invention provides compositions of small organic compounds that modulate circulating levels of low density lipoproteins by altering the conformation of the protein PCSK9. Binding these small organic compound ligands to PCSK9 alters the conformation of the protein, modifying the interaction between PCSK9 and an endogenous low density lipoprotein receptor, and can lead to reduced or increased levels of circulating LDL-cholesterol. High LDL- cholesterol levels are associated with increased risk for heart disease. Low LDL-cholesterol levels may be problematic in other conditions, such as liver dysfunction; thus, there is also utility for small organic compound ligands that can raise LDL levels.

Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors

Pensa, Anthony V.,Cinelli, Maris A.,Li, Huiying,Chreifi, Georges,Mukherjee, Paramita,Roman, Linda J.,Martásek, Pavel,Poulos, Thomas L.,Silverman, Richard B.

, p. 7146 - 7165 (2017/09/07)

Neuronal nitric oxide synthase (nNOS) is a target for development of antineurodegenerative agents. Most nNOS inhibitors mimic l-arginine and have poor bioavailability. 2-Aminoquinolines showed promise as bioavailable nNOS inhibitors but suffered from low

COMPOSITION AND METHODS OF USE OF TETRAHYDROISOQUINOLINE SMALL MOLECULES TO BIND AND MODULATE PCSK9 PROTEIN ACTIVITY

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Page/Page column 37; 38, (2017/03/14)

This invention is related to the field of PCSK9 biology and the composition and methods of use of small organic compounds as ligands for modulation of PCSK9 biological activity. In particular, the invention provides compositions of small organic compounds

BORON-CONTAINING SMALL MOLECULES AS ANTI-INFLAMMATORY AGENTS

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Paragraph 0164, (2015/04/15)

Compounds, pharmaceutical formulations, and methods of treating inflammatory conditions are disclosed.(F)

Synthesis of end-group functionalized P3HT: General protocol for P3HT/nanoparticle hybrids

Monnaie, Frederic,Brullot, Ward,Verbiest, Thierry,De Winter, Julien,Gerbaux, Pascal,Smeets, Alfons,Koeckelberghs, Guy

, p. 8500 - 8508 (2013/12/04)

Poly(3-hexylthiophene)s were synthesized with phosphonic ester, pyridine, thiol, and phenol end-groups using functionalized air-stable Ni initiators. The protected thiol- and phenol-functionalized P3HTs were converted into thiol and phenol P3HTs by quanti

PYRROLIDINE GPR40 MODULATORS

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, (2011/04/24)

The present invention provides compounds of Formula (I): or a stereoisomer, or a pharmaceutically acceptable salt thereof, wherein all of the variables are as defined herein. These compounds are GPR40 G protein-coupled receptor modulators which may be used as medicaments.

BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATMENT OF VALLINOID RECE TOR TRPVL RELATED DISORDERS

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Page/Page column 57-58, (2008/06/13)

The claimed invention provides benzimidazole derivatives antagonists of VRl, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds of Formula I may be used in the treatment of osteoarthritis,

BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS

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, (2008/06/13)

A superior LXR modulator is provided. A compound represented by the general formula (I): [wherein R1: -COR9 (wherein R9: alkyl, optionally substituted alkoxy or optionally substituted amino); R2: H, OH, alkoxy, optionally substituted amino, etc.; R3: H, optionally substituted alkyl, cycloalkyl, optionally substituted alkoxy, optionally substituted amino, halogeno, etc.; R4 and R5: H, optionally substituted alkyl, halogeno, etc.; R6 and R7: H, alkyl; R8: -X2R10 [wherein R10: -COR11 (wherein R11 : OH, optionally substituted alkoxy, optionally substituted amino, etc.), -SO2R12 (wherein R12: optionally substituted alkyl, optionally substituted amino, etc.), tetrazol-5-yl, etc.; X2: single bond, optionally substituted alkylene, etc.]; X1: -NH-, -O-, -S-, etc.; Y1: optionally substituted phenyl, optionally substituted 5- to 6-membered aromatic heterocyclyl; Y2: optionally substituted aryl, optionally substituted heterocyclyl, etc.] and the like is provided.

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