215800-25-2

Usage

Uses

Used in Pharmaceutical Industry:
2-(4-bromo-3-methylphenyl)acetonitrile is used as an intermediate in the production of various pharmaceuticals for its ability to be a building block in the synthesis of complex organic molecules. Its unique structure allows it to be a key component in the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 2-(4-bromo-3-methylphenyl)acetonitrile is utilized as an intermediate in the synthesis of agrochemicals, contributing to the development of effective pesticides and other agricultural chemicals that require its specific structural attributes.
Used in Organic Synthesis:
2-(4-bromo-3-methylphenyl)acetonitrile is used as a building block in organic synthesis for creating a variety of other organic compounds, showcasing its versatility in chemical reactions and its importance in the synthesis of specialty chemicals.
Used in Research and Development:
2-(4-bromo-3-methylphenyl)acetonitrile serves a crucial role in research and development, where it is used to explore new chemical reactions, understand structure-activity relationships, and innovate in the fields of pharmaceuticals and agrochemicals.

Upstream product

• 27561-51-9 1-bromo-4-(bromomethyl)-2-methylbenzene 
• 151-50-8 potassium cyanide 
• 148547-19-7 4-Bromo-3-methylbenzoic acid methyl ester 
• 149104-89-2 4-bromo-3-methylbenzylalcohol 
• 78775-11-8 3-methyl-4-bromobenzaldehyde 
• 773837-37-9 sodium cyanide 

Downstream Products

• 1006390-25-5 2-(4-bromo-3-methylphenyl)-2-methylpropanenitrile 
• 885681-93-6 methyl 2-(4-bromo-3-methylphenyl)acetate 
• 786625-94-3 C₉H₁₂BrN 
• 1818380-84-5 1-[3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]cyclopropanecarbonitrile 
• 1314760-71-8 1-(4-bromo-3-methyl-phenyl)cyclopropanecarbonitrile 

Relevant academic research and scientific papers

Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors

Neuronal nitric oxide synthase (nNOS) is a target for development of antineurodegenerative agents. Most nNOS inhibitors mimic l-arginine and have poor bioavailability. 2-Aminoquinolines showed promise as bioavailable nNOS inhibitors but suffered from low

COMPOSITION AND METHODS OF USE OF TETRAHYDROISOQUINOLINE SMALL MOLECULES TO BIND AND MODULATE PCSK9 PROTEIN ACTIVITY

This invention is related to the field of PCSK9 biology and the composition and methods of use of small organic compounds as ligands for modulation of PCSK9 biological activity. In particular, the invention provides compositions of small organic compounds

BENZIMIDAZOLE DERIVATIVES USEFUL IN TREATMENT OF VALLINOID RECE TOR TRPVL RELATED DISORDERS

The claimed invention provides benzimidazole derivatives antagonists of VRl, processes for their preparation, pharmaceutical compositions containing them and their use in therapy. The compounds of Formula I may be used in the treatment of osteoarthritis,

BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS

A superior LXR modulator is provided. A compound represented by the general formula (I): [wherein R1: -COR9 (wherein R9: alkyl, optionally substituted alkoxy or optionally substituted amino); R2: H, OH, alkoxy, optionally substituted amino, etc.; R3: H, optionally substituted alkyl, cycloalkyl, optionally substituted alkoxy, optionally substituted amino, halogeno, etc.; R4 and R5: H, optionally substituted alkyl, halogeno, etc.; R6 and R7: H, alkyl; R8: -X2R10 [wherein R10: -COR11 (wherein R11 : OH, optionally substituted alkoxy, optionally substituted amino, etc.), -SO2R12 (wherein R12: optionally substituted alkyl, optionally substituted amino, etc.), tetrazol-5-yl, etc.; X2: single bond, optionally substituted alkylene, etc.]; X1: -NH-, -O-, -S-, etc.; Y1: optionally substituted phenyl, optionally substituted 5- to 6-membered aromatic heterocyclyl; Y2: optionally substituted aryl, optionally substituted heterocyclyl, etc.] and the like is provided.

BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS

Disclosed is an excellent LXR modulator. Specifically disclosed is a compound represented by the general formula (I) below or the like. (I) [In the formula, R1 represents a -COR9 (wherein R9 represents an alkyl, optionally substituted alkoxy or optionally substituted amino); R2 represents an H, OH, alkoxy, optionally substituted amino or the like; R3 represents an H, optionally substituted alkyl, cycloalkyl, optionally substituted alkoxy, optionally substituted amino, halogeno or the like; R4 and R5 respectively represent an H, optionally substituted alkyl, halogeno or the like; R6 and R7 respectively represent an H or alkyl; R8 represents a -X2R10 [wherein R10 represents a -COR11 (wherein R11 represents an OH, optionally substituted alkoxy, optionally substituted amino or the like), -SO2R12 (wherein R12 represents an optionally substituted alkyl, optionally substituted amino or the like), tetrazole-5-yl or the like; and X2 represents a single bond, optionally substituted alkylene or the like]; X1 represents an -NH-, -O-, -S- or the like; Y1 represents an optionally substituted phenyl or optionally substituted 5-membered or 6-membered aromatic heterocyclyl; and Y2 represents an optionally substituted aryl, substituted heterocyclyl or the like.]