benzyl ((S)-1-((1S,2R,4R)-2-acetamido-4-(tert-butylamino)cyclohexyl)-2-oxopyrrolidin-3-yI)carbamate

Base Information

• Chemical Name: benzyl ((S)-1-((1S,2R,4R)-2-acetamido-4-(tert-butylamino)cyclohexyl)-2-oxopyrrolidin-3-yI)carbamate
• CAS No.: 1004536-73-5
• Molecular Formula: C₂₄H₃₆N₄O₄
• Molecular Weight: 444.574

Synonyms:benzyl ((S)-1-((1S,2R,4R)-2-acetamido-4-(tert-butylamino)cyclohexyl)-2-oxopyrrolidin-3-yI)carbamate

Chemical Property of benzyl ((S)-1-((1S,2R,4R)-2-acetamido-4-(tert-butylamino)cyclohexyl)-2-oxopyrrolidin-3-yI)carbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzyl ((S)-1-((1S,2R,4R)-2-acetamido-4-(tert-butylamino)cyclohexyl)-2-oxopyrrolidin-3-yI)carbamate

There total 19 articles about benzyl ((S)-1-((1S,2R,4R)-2-acetamido-4-(tert-butylamino)cyclohexyl)-2-oxopyrrolidin-3-yI)carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

benzyl (S)-1-((1S,2R)-2-acetamido-4-oxocyclohexyl)-2-oxopyrrolidin-3-ylcarbamate (1004536-70-2) + tert-butylamine (75-64-9) → benzyl ((S)-1-((1S,2R,4R)-2-acetamido-4-(tert-butylamino)cyclohexyl)-2-oxopyrrolidin-3-yI)carbamate (1004536-73-5)

Guidance literature:

benzyl (S)-1-((1S,2R)-2-acetamido-4-oxocyclohexyl)-2-oxopyrrolidin-3-ylcarbamate; tert-butylamine; titanium(IV)isopropoxide; titanium tetrachloride; In dichloromethane; at -50 - 20 ℃; for 2.16667h;

With dimethylsulfide borane complex; In dichloromethane; at 10 - 20 ℃; for 5h;

Reference yield: 78.0%

benzyl (S)-1-((1S,2R)-2-acetamido-4-oxocyclohexyl)-2-oxopyrrolidin-3-ylcarbamate (1004536-70-2) + tert-butylamine (75-64-9) → benzyl ((S)-1-((1S,2R,4R)-2-acetamido-4-(tert-butylamino)cyclohexyl)-2-oxopyrrolidin-3-yI)carbamate (1004536-73-5) + C24H36N4O4

Guidance literature:

benzyl (S)-1-((1S,2R)-2-acetamido-4-oxocyclohexyl)-2-oxopyrrolidin-3-ylcarbamate; tert-butylamine; In dichloromethane;

With titanium(IV) isopropylate; dimethylsulfide borane complex; titanium tetrachloride; In dichloromethane; at 20 ℃; for 16h; Reagent/catalyst; Catalytic behavior;

DOI:10.1021/acsmedchemlett.1c00082

Reference yield:

C31H44N4O5 → benzyl ((S)-1-((1S,2R,4R)-2-acetamido-4-(tert-butylamino)cyclohexyl)-2-oxopyrrolidin-3-yI)carbamate (1004536-73-5)

Guidance literature:

With acetic acid; In toluene; at 57 ℃; for 5h;

upstream raw materials:

benzyl (S)-1-((1S,2R)-2-acetamido-4-oxocyclohexyl)-2-oxopyrrolidin-3-ylcarbamate

tert-butylamine

((S)-4-Oxo-cyclohex-2-enyl)-carbamic acid tert-butyl ester

Z-Asp-OBn

Downstream raw materials:

N-((1R,2S,5R)-2-((S)-3-amino-2-oxopyrrolidin-1-yl)-5-(tert-butylamino)cyclohexyl)acetamide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1004536-73-5 benzyl ((S)-1-((1S,2R,4R)-2-acetamido-4-(tert-butylamino)cyclohexyl)-2-oxopyrrolidin-3-yI)carbamate

Send

Send

Metric Ton KG G Pound L ML

Send

Send