(S)-4-Methyl-4-phenyl-2-oxazolidinone

Base Information

Chemical Name:(S)-4-Methyl-4-phenyl-2-oxazolidinone
CAS No.:13398-55-5
Molecular Formula:C₁₀H₁₁NO₂
Molecular Weight:177.203
Hs Code.:
DSSTox Substance ID:DTXSID501282604
Nikkaji Number:J1.421.440B

Synonyms:13398-55-5;SCHEMBL1438983;DTXSID501282604;(S)-4-Methyl-4-phenyl-2-oxazolidinone;(4S)-4-Methyl-4-phenyl-2-oxazolidinone

Suppliers and Price of (S)-4-Methyl-4-phenyl-2-oxazolidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of (S)-4-Methyl-4-phenyl-2-oxazolidinone

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:177.078978594
Heavy Atom Count:13
Complexity:211

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1(COC(=O)N1)C2=CC=CC=C2
Isomeric SMILES:C[C@@]1(COC(=O)N1)C2=CC=CC=C2

Technology Process of (S)-4-Methyl-4-phenyl-2-oxazolidinone

There total 4 articles about (S)-4-Methyl-4-phenyl-2-oxazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 208938-37-8
tert-Butyl-((S)-2-isocyanato-2-phenyl-propoxy)-dimethyl-silane

: 13398-55-5
(S)-4-methyl-4-phenyloxazolidin-2-one

Guidance literature:: With boron trifluoride diethyl etherate; In tetrahydrofuran;
DOI:10.1016/S0040-4039(98)00576-0

Reference yield:

: 208938-33-4
(S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-2-phenyl-propionaldehyde

: 13398-55-5
(S)-4-methyl-4-phenyloxazolidin-2-one

Guidance literature:: Multi-step reaction with 3 steps

1: 87 percent / RuO₄, NaIO₄ / CCl₄; acetonitrile; H₂O

2: 62 percent / DPPA, Et₃N / toluene / Heating

3: 98 percent / BF₃*OEt₂ / tetrahydrofuran

With sodium periodate; ruthenium tetroxide; boron trifluoride diethyl etherate; diphenyl-phosphinic acid; triethylamine; In tetrahydrofuran; tetrachloromethane; water; toluene; acetonitrile;
DOI:10.1016/S0040-4039(98)00576-0

Reference yield:

: 208938-35-6
(S)-3-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-2-phenyl-propionic acid

: 13398-55-5
(S)-4-methyl-4-phenyloxazolidin-2-one

Guidance literature:: Multi-step reaction with 2 steps

1: 62 percent / DPPA, Et₃N / toluene / Heating

2: 98 percent / BF₃*OEt₂ / tetrahydrofuran

With boron trifluoride diethyl etherate; diphenyl-phosphinic acid; triethylamine; In tetrahydrofuran; toluene;
DOI:10.1016/S0040-4039(98)00576-0