4-<2-(3,4,5-trimethoxyphenyl)ethenyl>benzoic acid methyl ester

Base Information

• Chemical Name: 4-<2-(3,4,5-trimethoxyphenyl)ethenyl>benzoic acid methyl ester
• CAS No.: 360789-58-8
• Molecular Formula: C₁₉H₂₀O₅
• Molecular Weight: 328.365
• Mol file: 360789-58-8.mol

Synonyms:4-<2-(3,4,5-trimethoxyphenyl)ethenyl>benzoic acid methyl ester

Chemical Property of 4-<2-(3,4,5-trimethoxyphenyl)ethenyl>benzoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-<2-(3,4,5-trimethoxyphenyl)ethenyl>benzoic acid methyl ester

There total 2 articles about 4-<2-(3,4,5-trimethoxyphenyl)ethenyl>benzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

3,4,5-trimethoxy-benzaldehyde (86-81-7) + 4-methoxycarbonylbenzyltriphenylphosphonium bromide (1253-46-9) → 4-<2-(3,4,5-trimethoxyphenyl)ethenyl>benzoic acid methyl ester (360789-58-8)

Guidance literature:

4-methoxycarbonylbenzyltriphenylphosphonium bromide; With 18-crown-6 ether; potassium carbonate; In tetrahydrofuran; dichloromethane; for 0.0833333h;

3,4,5-trimethoxy-benzaldehyde; In tetrahydrofuran; dichloromethane; for 10h; Heating;

DOI:10.1021/ja0394434

Reference yield:

methanol (67-56-1) + 3,4,5-trimethoxy-benzaldehyde (86-81-7) + p-Toluic acid (99-94-5) → 4-<2-(3,4,5-trimethoxyphenyl)ethenyl>benzoic acid methyl ester (360789-58-8)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; sulfuric acid; toluene-4-sulfonic acid; lithium diisopropyl amide; Yield given. Multistep reaction;

DOI:10.1080/00397919508011404

Reference yield: 90.0%

4-<2-(3,4,5-trimethoxyphenyl)ethenyl>benzoic acid methyl ester (360789-58-8) → (E)-4-[2-(3,4,5-trimethoxyphenyl)vinyl]benzoic acid (360789-59-9)

Guidance literature:

With potassium hydroxide; In ethanol; for 3h; Heating;

DOI:10.1021/ja0394434

upstream raw materials:

methanol

3,4,5-trimethoxy-benzaldehyde

p-Toluic acid

4-methoxycarbonylbenzyltriphenylphosphonium bromide

Downstream raw materials:

4-<2-(3,4,5-trimethoxyphenyl)ethyl>-benzoic acid methyl ester

(E)-4-[2-(3,4,5-trimethoxyphenyl)vinyl]benzoic acid

N-(3-hydroxy-propyl)-4-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-benzamide