N-Mor-rhodamine 110

Base Information

• Chemical Name: N-Mor-rhodamine 110
• CAS No.: 628302-72-7
• Molecular Formula: C₂₅H₂₁N₃O₅
• Molecular Weight: 443.459
• Mol file: 628302-72-7.mol

Synonyms:N-Mor-rhodamine 110

Chemical Property of N-Mor-rhodamine 110

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-Mor-rhodamine 110

There total 1 articles about N-Mor-rhodamine 110 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-morpholinocarbonyl chloride (15159-40-7) + 3',6'-diamino-spiro[phthalan-1,9'-xanthen]-3-one (509-72-8) → N-Mor-rhodamine 110 (628302-72-7)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; Inert atmosphere;

DOI:10.1021/ja203661j

Reference yield:

N-Mor-rhodamine 110 (628302-72-7) + Cbz-Asp-(OtBu)-Glu(OtBu)-V-(O-Boc-D)-OH → C63H77N7O17

Guidance literature:

Reference yield:

N-Mor-rhodamine 110 (628302-72-7) → 2-(3-iminio-6-(morpholine-4-carboxamido)-3H-xanthen-9-yl)benzoate

Guidance literature:

Multi-step reaction with 2 steps

1.1: trifluoroacetic acid / dichloromethane; acetonitrile / 0 °C / Inert atmosphere

1.2: 2 h / 20 °C / Inert atmosphere

1.3: 1 h / 20 °C / Inert atmosphere

2.1: hydrogen sulfide / 1 h / 25 °C / pH 7.4 / HEPES buffer

With hydrogen sulfide; trifluoroacetic acid; In dichloromethane; acetonitrile; 1.1: Sandmeyer reaction / 1.2: Sandmeyer reaction / 1.3: Sandmeyer reaction;

DOI:10.1021/ja203661j

upstream raw materials:

4-morpholinocarbonyl chloride

3',6'-diamino-spiro[phthalan-1,9'-xanthen]-3-one

Refernces