((1S,2R,3S)-3-(2-((4-methoxybenzyl)oxy)ethyl)-2-((Z)-pent-2-en-1-yl)-1-((triethylsilyl)oxy))cyclopentane

Base Information

Chemical Name:((1S,2R,3S)-3-(2-((4-methoxybenzyl)oxy)ethyl)-2-((Z)-pent-2-en-1-yl)-1-((triethylsilyl)oxy))cyclopentane
CAS No.:1382669-48-8
Molecular Formula:C₂₆H₄₄O₃Si
Molecular Weight:432.719
Hs Code.:

Synonyms:((1S,2R,3S)-3-(2-((4-methoxybenzyl)oxy)ethyl)-2-((Z)-pent-2-en-1-yl)-1-((triethylsilyl)oxy))cyclopentane

Suppliers and Price of ((1S,2R,3S)-3-(2-((4-methoxybenzyl)oxy)ethyl)-2-((Z)-pent-2-en-1-yl)-1-((triethylsilyl)oxy))cyclopentane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ((1S,2R,3S)-3-(2-((4-methoxybenzyl)oxy)ethyl)-2-((Z)-pent-2-en-1-yl)-1-((triethylsilyl)oxy))cyclopentane

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ((1S,2R,3S)-3-(2-((4-methoxybenzyl)oxy)ethyl)-2-((Z)-pent-2-en-1-yl)-1-((triethylsilyl)oxy))cyclopentane

There total 7 articles about ((1S,2R,3S)-3-(2-((4-methoxybenzyl)oxy)ethyl)-2-((Z)-pent-2-en-1-yl)-1-((triethylsilyl)oxy))cyclopentane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1382669-45-5
((1S,2R,3S)-3-(2-((4-methoxybenzyl)oxy)ethyl)-2-(2-((triethylsilyl)oxy)ethyl)-1-((triethylsilyl)oxy))cyclopentane

: 6228-47-3
n-propyltriphenylphosphonium bromide

: 1382669-48-8
((1S,2R,3S)-3-(2-((4-methoxybenzyl)oxy)ethyl)-2-((Z)-pent-2-en-1-yl)-1-((triethylsilyl)oxy))cyclopentane

Guidance literature:: ((1S,2R,3S)-3-(2-((4-methoxybenzyl)oxy)ethyl)-2-(2-((triethylsilyl)oxy)ethyl)-1-((triethylsilyl)oxy))cyclopentane; With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -78 ℃;

With triethylamine; In dichloromethane;

n-propyltriphenylphosphonium bromide; With sodium hexamethyldisilazane; In tetrahydrofuran; dichloromethane;
DOI:10.1007/s00726-011-0925-z

Reference yield:

: 1382669-33-1
2-((1R,5S)-5-(2-((4-methoxybenzyl)oxy)ethyl)cyclopent-2-en-1-yl)-N,N-dimethylacetamide

: 1382669-48-8
((1S,2R,3S)-3-(2-((4-methoxybenzyl)oxy)ethyl)-2-((Z)-pent-2-en-1-yl)-1-((triethylsilyl)oxy))cyclopentane

Guidance literature:: Multi-step reaction with 5 steps

1: iodine / tetrahydrofuran; water / 3 h / 20 °C

2: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride / benzene / Heating

3: lithium aluminium tetrahydride / diethyl ether / 1 h / 0 - 20 °C

4: 1H-imidazole / N,N-dimethyl-formamide / 18 h / 20 °C

5: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 °C

With 1H-imidazole; lithium aluminium tetrahydride; oxalyl dichloride; 2,2'-azobis(isobutyronitrile); iodine; tri-n-butyl-tin hydride; dimethyl sulfoxide; In tetrahydrofuran; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; benzene; 5: Wittig reaction;
DOI:10.1007/s00726-011-0925-z

Reference yield:

: 1382669-36-4
(3aR,4R,6R,6aR)-6-iodo-4-(2-((4-methoxybenzyl)oxy)ethyl)hexahydro-2H-cyclopenta[b]furan-2-one

: 1382669-48-8
((1S,2R,3S)-3-(2-((4-methoxybenzyl)oxy)ethyl)-2-((Z)-pent-2-en-1-yl)-1-((triethylsilyl)oxy))cyclopentane

Guidance literature:: Multi-step reaction with 4 steps

1: 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride / benzene / Heating

2: lithium aluminium tetrahydride / diethyl ether / 1 h / 0 - 20 °C

3: 1H-imidazole / N,N-dimethyl-formamide / 18 h / 20 °C

4: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / -78 °C

With 1H-imidazole; lithium aluminium tetrahydride; oxalyl dichloride; 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; dimethyl sulfoxide; In diethyl ether; dichloromethane; N,N-dimethyl-formamide; benzene; 4: Wittig reaction;
DOI:10.1007/s00726-011-0925-z