Technology Process of C19H16O6
There total 9 articles about C19H16O6 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
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Multi-step reaction with 5 steps
1: potassium carbonate / acetone / 3 h / 20 °C / Inert atmosphere
2: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C
3: palladium 10% on activated carbon; hydrogen / tetrahydrofuran / 3 h / 20 °C / 760.05 Torr / Inert atmosphere
4: trichlorophosphate / ethyl acetate / 5 h / 20 °C / Inert atmosphere
5: potassium hydroxide / methanol / 2 h / 70 °C
With
palladium 10% on activated carbon; hydrogen; sodium hydride; potassium carbonate; potassium hydroxide; trichlorophosphate;
In
tetrahydrofuran; methanol; ethyl acetate; N,N-dimethyl-formamide; acetone;
2: |Aldol Condensation;
DOI:10.1021/acs.jnatprod.0c00830
- Guidance literature:
-
Multi-step reaction with 5 steps
1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 0 °C
2: palladium 10% on activated carbon; hydrogen / tetrahydrofuran / 16 h / 20 °C / 760.05 Torr / Inert atmosphere
3: trichlorophosphate / ethyl acetate / 3 h / 20 °C / Inert atmosphere
4: potassium hydroxide / methanol / 2 h / 70 °C / Inert atmosphere
5: boron trifluoride diethyl etherate / N,N-dimethyl-formamide / 2 h / 80 °C / Inert atmosphere
With
palladium 10% on activated carbon; boron trifluoride diethyl etherate; hydrogen; sodium hydride; potassium hydroxide; trichlorophosphate;
In
tetrahydrofuran; methanol; ethyl acetate; N,N-dimethyl-formamide;
1: |Aldol Condensation / 3: |Vilsmeier-Haack Formylation;
DOI:10.1021/acs.jnatprod.0c00830