3-(Bromomethyl)-1,5-diphenylpyrazole

Base Information

Chemical Name:3-(Bromomethyl)-1,5-diphenylpyrazole
CAS No.:781663-74-9
Molecular Formula:C16H13 Br N2
Molecular Weight:313.197
Hs Code.:2933199090
DSSTox Substance ID:DTXSID80458126
Wikidata:Q82281279
Mol file:781663-74-9.mol

Synonyms:781663-74-9;SCHEMBL9349328;DTXSID80458126;AG-H-13582

Suppliers and Price of 3-(Bromomethyl)-1,5-diphenylpyrazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-BROMOMETHYL-N,5-DIPHENYL-PYRAZOLE 95.00%
5MG
$ 496.44

Total 1 raw suppliers

Chemical Property of 3-(Bromomethyl)-1,5-diphenylpyrazole

Chemical Property:

Vapor Pressure:2.22E-07mmHg at 25°C
Refractive Index:1.633
Boiling Point:435.5°C at 760 mmHg
Flash Point:217.2°C
PSA：17.82000
Density:1.34g/cm³
LogP:4.43420
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:312.02621
Heavy Atom Count:19
Complexity:272

Purity/Quality:: 3-BROMOMETHYL-N,5-DIPHENYL-PYRAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CC(=NN2C3=CC=CC=C3)CBr

Technology Process of 3-(Bromomethyl)-1,5-diphenylpyrazole

There total 4 articles about 3-(Bromomethyl)-1,5-diphenylpyrazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 945984-78-1
(1,5-diphenyl-1H-pyrazol-3-yl)-methanol

: 781663-74-9
3-bromomethyl-1,5-diphenyl-1H-pyrazole

Guidance literature:: (1,5-diphenyl-1H-pyrazol-3-yl)-methanol; With triphenylphosphine; In dichloromethane; at 0 ℃; for 0.5h;

With N-Bromosuccinimide; In dichloromethane; at 20 ℃; for 15h;
DOI:10.1021/jm0407761

Reference yield:

: 17355-75-8
ethyl 1,5-diphenyl-1H-pyrazole-3-carboxylate

: 781663-74-9
3-bromomethyl-1,5-diphenyl-1H-pyrazole

Guidance literature:: Multi-step reaction with 2 steps

1.1: LiBH₄ / tetrahydrofuran / 72 h / 20 °C

2.1: Ph₃P / CH₂Cl₂ / 0.5 h / 0 °C

2.2: 340 mg / N-bromosuccinimide / CH₂Cl₂ / 15 h / 20 °C

With lithium borohydride; triphenylphosphine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm0407761

Reference yield:

: 88330-79-4,244277-46-1
ethyl-(Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoate

: 781663-74-9
3-bromomethyl-1,5-diphenyl-1H-pyrazole

Guidance literature:: Multi-step reaction with 3 steps

1.1: 76 percent / ethanol / 3 h / Heating

2.1: LiBH₄ / tetrahydrofuran / 72 h / 20 °C

3.1: Ph₃P / CH₂Cl₂ / 0.5 h / 0 °C

3.2: 340 mg / N-bromosuccinimide / CH₂Cl₂ / 15 h / 20 °C

With lithium borohydride; triphenylphosphine; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1021/jm0407761