N-(buta-2,3-dienyl)-N-t-butoxycarbonyl-4-methylphenylsulfonamide

Base Information

• Chemical Name: N-(buta-2,3-dienyl)-N-t-butoxycarbonyl-4-methylphenylsulfonamide
• CAS No.: 942509-44-6
• Molecular Formula: C₁₆H₂₁NO₄S
• Molecular Weight: 323.413
• Mol file: 942509-44-6.mol

Synonyms:N-(buta-2,3-dienyl)-N-t-butoxycarbonyl-4-methylphenylsulfonamide

Chemical Property of N-(buta-2,3-dienyl)-N-t-butoxycarbonyl-4-methylphenylsulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(buta-2,3-dienyl)-N-t-butoxycarbonyl-4-methylphenylsulfonamide

There total 1 articles about N-(buta-2,3-dienyl)-N-t-butoxycarbonyl-4-methylphenylsulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + N-(tert-butoxycarbonyl)-4-methyl-N-prop-2-ynylbenzenesulfonamide (189031-66-1) → N-(buta-2,3-dienyl)-N-t-butoxycarbonyl-4-methylphenylsulfonamide (942509-44-6)

Guidance literature:

With diisopropylamine; copper(I) bromide; In 1,4-dioxane; for 8h; Heating;

DOI:10.1021/jo0700528

Reference yield: 93.0%

N-(buta-2,3-dienyl)-N-t-butoxycarbonyl-4-methylphenylsulfonamide (942509-44-6) + (R)-2-(prop-1-en-2-yl)-1-tosylaziridine → (R,E)-tert-butyl (2-(4-(prop-1-en-2-yl)-1-tosylpyrrolidin-2-ylidene)ethyl)(tosyl)carbamate

Guidance literature:

With di-μ-chlorobis(norbornadiene)dirhodium(I); silver trifluoromethanesulfonate; In acetone; at 0 ℃; for 2h; stereoselective reaction; Inert atmosphere;

DOI:10.1002/anie.201605530

Reference yield: 80.0%

N-(buta-2,3-dienyl)-N-t-butoxycarbonyl-4-methylphenylsulfonamide (942509-44-6) → N-(buta-2,3-dien-1-yl)-4-methylbenzenesulfonamide (346587-69-7)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 12h;

DOI:10.1021/jo0700528

upstream raw materials:

formaldehyd

N-(tert-butoxycarbonyl)-4-methyl-N-prop-2-ynylbenzenesulfonamide

Downstream raw materials:

N-(buta-2,3-dien-1-yl)-4-methylbenzenesulfonamide

N-(buta-2,3-dien-1-yl)-4-methyl-N-(3-phenylprop-2-yn-1-yl)benzenesulfonamide

N-buta-2,3-dienyl-N-cinnamoyl-4-methylphenylsulfonamide

7-methylene-8-(2'-N-tert-butoxycarbonyl-N-tosylamidoeth-1'(E)-ylidene)-4,4-bis(phenylsulfonyl)bicyclo[4.4.0]decene