4-(Piperidine-1-sulfonyl)phenol

Base Information

Chemical Name:4-(Piperidine-1-sulfonyl)phenol
CAS No.:99986-71-7
Molecular Formula:C₁₁H₁₅NO₃S
Molecular Weight:241.311
Hs Code.:
European Community (EC) Number:868-876-4
ChEMBL ID:CHEMBL4562537

Synonyms:4-(piperidine-1-sulfonyl)phenol;99986-71-7;4-piperidin-1-ylsulfonylphenol;Oprea1_409257;CHEMBL4562537;SCHEMBL18031181;AKOS008966289;4-(piperidine-1-sulfonyl)phenol, AldrichCPR;EN300-58925;Z56794392

Suppliers and Price of 4-(Piperidine-1-sulfonyl)phenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 4-(Piperidine-1-sulfonyl)phenol

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:241.07726451
Heavy Atom Count:16
Complexity:309

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(CC1)S(=O)(=O)C2=CC=C(C=C2)O

Technology Process of 4-(Piperidine-1-sulfonyl)phenol

There total 3 articles about 4-(Piperidine-1-sulfonyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 35088-89-2
1-(4-methoxybenzenesulfonyl)-piperidine

: 99986-71-7
4-(piperidin-1-ylsulfonyl)phenol

Guidance literature:: With boron tribromide; In dichloromethane; at 0 - 20 ℃; for 12h;
DOI:10.1021/acsmedchemlett.5b00202

Reference yield:

: 98-68-0
4-methoxy-phenyl-sulphonyl chloride

: 99986-71-7
4-(piperidin-1-ylsulfonyl)phenol

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; triethylamine / dichloromethane / 12 h / 40 °C / Inert atmosphere

2: boron tribromide / dichloromethane / 12 h / 0 - 20 °C

With dmap; boron tribromide; triethylamine; In dichloromethane;
DOI:10.1021/acsmedchemlett.5b00202

Reference yield:

: 110-89-4
piperidine

: 99986-71-7
4-(piperidin-1-ylsulfonyl)phenol

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; triethylamine / dichloromethane / 12 h / 40 °C / Inert atmosphere

2: boron tribromide / dichloromethane / 12 h / 0 - 20 °C

With dmap; boron tribromide; triethylamine; In dichloromethane;
DOI:10.1021/acsmedchemlett.5b00202