(3-Bromo-5-methylphenoxy)(tert-butyl)dimethylsilane

Base Information

Chemical Name:(3-Bromo-5-methylphenoxy)(tert-butyl)dimethylsilane
CAS No.:136386-75-9
Molecular Formula:C₁₃H₂₁BrOSi
Molecular Weight:301.299
Hs Code.:
DSSTox Substance ID:DTXSID901169832
Nikkaji Number:J3.564.110F

Synonyms:(3-bromo-5-methylphenoxy)(tert-butyl)dimethylsilane;136386-75-9;Benzene, 1-bromo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-methyl-;SCHEMBL4406786;KJBOBQDNPJSPRN-UHFFFAOYSA-N;DTXSID901169832;F97763;EN300-22882707;(3-Bromo-5-methyl-phenoxy)-tert-butyldimethylsilane;1-Bromo-3-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5-methylbenzene

Suppliers and Price of (3-Bromo-5-methylphenoxy)(tert-butyl)dimethylsilane

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of (3-Bromo-5-methylphenoxy)(tert-butyl)dimethylsilane

Chemical Property:

Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:300.05450
Heavy Atom Count:16
Complexity:235

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=CC(=C1)Br)O[Si](C)(C)C(C)(C)C

Technology Process of (3-Bromo-5-methylphenoxy)(tert-butyl)dimethylsilane

There total 5 articles about (3-Bromo-5-methylphenoxy)(tert-butyl)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 74204-00-5
3-bromo-5-methylphenol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 136386-75-9
(3-bromo-5-methyl-phenoxy)-tert-butyl-dimethyl-silane

Guidance literature:: With 1H-imidazole; dmap; In dichloromethane; at 0 - 20 ℃; for 18h;
DOI:10.1021/acs.orglett.6b02424

Reference yield:

: 58169-99-6
2,3,4,6-tetrabromo-5-methyl-phenol

: 18162-48-6
tert-butyldimethylsilyl chloride

: 136386-75-9
(3-bromo-5-methyl-phenoxy)-tert-butyl-dimethyl-silane

: tert-butyl-(3-iodo-5-methyl-phenoxy)-dimethyl-silane

Guidance literature:: 2,3,4,6-tetrabromo-5-methyl-phenol; With hydrogen iodide; In water; Heating;

tert-butyldimethylsilyl chloride; With 1H-imidazole; dmap; In dichloromethane; at 0 - 23 ℃; for 18h; Title compound not separated from byproducts;
DOI:10.1021/jo049426c

Reference yield:

: 34946-83-3
2,4,4,6-tetrabromo-3-methyl-cyclohexa-2,5-dienone

: 136386-75-9
(3-bromo-5-methyl-phenoxy)-tert-butyl-dimethyl-silane

Guidance literature:: Multi-step reaction with 2 steps

1.1: 57 percent / sulfuric acid / 16 h

2.1: HI / H₂O / Heating

2.2: 2,6-lutidine

With sulfuric acid; hydrogen iodide; In water;
DOI:10.1021/jo049426c