2-[(4R,5R)-2,2-Dimethyl-5-(2,6,6-trimethyl-5-oxo-cyclohex-1-enyl)-[1,3]dioxolan-4-yl]-3,5-dimethoxy-benzaldehyde

Base Information

Chemical Name:2-[(4R,5R)-2,2-Dimethyl-5-(2,6,6-trimethyl-5-oxo-cyclohex-1-enyl)-[1,3]dioxolan-4-yl]-3,5-dimethoxy-benzaldehyde
CAS No.:173073-87-5
Molecular Formula:C₂₃H₃₀O₆
Molecular Weight:402.488
Hs Code.:

Synonyms:2-[(4R,5R)-2,2-Dimethyl-5-(2,6,6-trimethyl-5-oxo-cyclohex-1-enyl)-[1,3]dioxolan-4-yl]-3,5-dimethoxy-benzaldehyde

Suppliers and Price of 2-[(4R,5R)-2,2-Dimethyl-5-(2,6,6-trimethyl-5-oxo-cyclohex-1-enyl)-[1,3]dioxolan-4-yl]-3,5-dimethoxy-benzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[(4R,5R)-2,2-Dimethyl-5-(2,6,6-trimethyl-5-oxo-cyclohex-1-enyl)-[1,3]dioxolan-4-yl]-3,5-dimethoxy-benzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[(4R,5R)-2,2-Dimethyl-5-(2,6,6-trimethyl-5-oxo-cyclohex-1-enyl)-[1,3]dioxolan-4-yl]-3,5-dimethoxy-benzaldehyde

There total 6 articles about 2-[(4R,5R)-2,2-Dimethyl-5-(2,6,6-trimethyl-5-oxo-cyclohex-1-enyl)-[1,3]dioxolan-4-yl]-3,5-dimethoxy-benzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 173074-12-9
2-[(4R,5R)-2,2-Dimethyl-5-(6,6,8-trimethyl-1,4-dithia-spiro[4.5]dec-7-en-7-yl)-[1,3]dioxolan-4-yl]-3,5-dimethoxy-benzaldehyde

: 173073-87-5
2-[(4R,5R)-2,2-Dimethyl-5-(2,6,6-trimethyl-5-oxo-cyclohex-1-enyl)-[1,3]dioxolan-4-yl]-3,5-dimethoxy-benzaldehyde

Guidance literature:: With calcium carbonate; mercury dichloride; In water; acetonitrile; for 13h; Ambient temperature;
DOI:10.1021/jo9519367

Reference yield:

: 150966-58-8
5,5-(ethylenedioxy)-2,,6,6-trimethyl-1-iodocyclohexene

: 173073-87-5
2-[(4R,5R)-2,2-Dimethyl-5-(2,6,6-trimethyl-5-oxo-cyclohex-1-enyl)-[1,3]dioxolan-4-yl]-3,5-dimethoxy-benzaldehyde

Guidance literature:: Multi-step reaction with 6 steps

1: BF₃*OEt₂ / CH₂Cl₂ / 3 h / Ambient temperature

2: 1.) t-BuLi / 1) THF, pentane, -78 deg C, 30 min; 2) THF, pentane, -78 deg C, 30 min

3: 96 percent / PPTS / CH₂Cl₂ / 3.5 h / 0 °C

4: tetrabutylammonium fluoride / tetrahydrofuran / 0.5 h / Ambient temperature

5: MnO₂ / benzene / 19 h / Ambient temperature

6: 71 percent / CaCO₃, HgCl₂ / acetonitrile; H₂O / 13 h / Ambient temperature

With manganese(IV) oxide; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; tert.-butyl lithium; pyridinium p-toluenesulfonate; calcium carbonate; mercury dichloride; In tetrahydrofuran; dichloromethane; water; acetonitrile; benzene;
DOI:10.1021/jo9519367

Reference yield:

: 173073-81-9
7-Iodo-6,6,8-trimethyl-1,4-dithia-spiro[4.5]dec-7-ene

: 173073-87-5
2-[(4R,5R)-2,2-Dimethyl-5-(2,6,6-trimethyl-5-oxo-cyclohex-1-enyl)-[1,3]dioxolan-4-yl]-3,5-dimethoxy-benzaldehyde

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) t-BuLi / 1) THF, pentane, -78 deg C, 30 min; 2) THF, pentane, -78 deg C, 30 min

2: 96 percent / PPTS / CH₂Cl₂ / 3.5 h / 0 °C

3: tetrabutylammonium fluoride / tetrahydrofuran / 0.5 h / Ambient temperature

4: MnO₂ / benzene / 19 h / Ambient temperature

5: 71 percent / CaCO₃, HgCl₂ / acetonitrile; H₂O / 13 h / Ambient temperature

With manganese(IV) oxide; tetrabutyl ammonium fluoride; tert.-butyl lithium; pyridinium p-toluenesulfonate; calcium carbonate; mercury dichloride; In tetrahydrofuran; dichloromethane; water; acetonitrile; benzene;
DOI:10.1021/jo9519367